Table 1 S. pneumoniae (lytA) and H. influenzae (hpd) detection from DBS and NP swabs collected from children with pneumonia and healthy children from a rural area in Mozambique, 2015
Children with pneumonia | Healthy children | P value | |
|---|---|---|---|
N = 205 n(%) | N = 120 n(%) | ||
Dried Blood Spot PCR results | |||
lytA positive only | 13(6.3) | 21(17.5) | 0.001 |
hpd positive only | 18(8.8) | 15(12.5) | 0.11 |
lytA + hpd positive | 29(14.2) | 56(46.7) | < 0.001 |
Negative | 145(70.7) | 28(23.3) | < 0.001 |
NP swab culture resultsa | |||
S. pneumoniae only | 43(20.9) | 25(20.8) | 0.9 |
H. influenzae only | 14(6.8) | 9(7.6) | 0.8 |
S. pneumoniae + H. influenzae | 102(49.8) | 65(54.2) | 0.4 |
Negative | 45(22.0) | 21(17.7) | 0.35 |
NP-swab qPCR results from culture negative specimens | |||
n/N (%) | n/N(%) | P value | |
lytA positive | 19/60(31.7) | 7/30(23.3) | 0.41 |
hpd positive | 51/89(57.3) | 23/46(50.0) | 0.42 |