Combination of gamma-glutamyl transferase and liver stiffness measurement for biliary atresia screening at different ages: a retrospective analysis of 282 infants

Table 3 The ROC curve analysis results of GGT and LSM

		AUC	Youden index	95% CI	Cut-off value	sensitivity	specificity	PPV	NPV
All patients	GGT, U/L	0.914	0.739	0.881–0.947	192.5	0.889	0.850	0.845	0.893
All patients	LSM, kPa	0.771	0.434	0.715–0.825	9.5	0.733	0.701	0.692	0.741
Group A (≤60d)	GGT, U/L	0.919	0.812	0.861–0.977	191.2	0.892	0.920	0.943	0.852
Group A (≤60d)	LSM, kPa	0.761	0.458	0.671–0.850	7.5	0.878	0.580	0.756	0.763
Group B (61-90d)	GGT, U/L	0.921	0.666	0.877–0.966	213.2	0.852	0.814	0.797	0.892
Group B (61-90d)	LSM, kPa	0.865	0.646	0.798–0.932	10.0	0.889	0.757	0.738	0.898
Group C (91-120d)	GGT, U/L	0.963	0.926	0.903–1.000	281.5	1.000	0.926	0.778	1.000
Group C (91-120d)	LSM, kPa	0.905	0.741	0.800–1.000	11.0	1.000	0.741	0.636	1.000

CI Confidence interval, PPV Positive predictive value, NPV Negative predictive value, LSM Liver stiffness measurement, GGT Gamma-glutamyl transferase, ROC The receiver operating characteristic, AUC The area under the ROC curve

ISSN: 1471-2431