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Table 2 Bile acid assay of derivation cohort and normal controls

From: Development and validation of bile acid profile-based scoring system for identification of biliary atresia: a prospective study

 BA (n = 34)Non-BA (n = 32)Control (n = 37)Pa
CA (ng/ml)9 (8, 13)c10.3 (8, 15)d97 (60, 172)< 0.001
CDCA (ng/ml)16 (1, 21) b, c26 (14, 37)d216 (108, 324)< 0.001
GDCA (ng/ml)5.2 (2.0, 7.2)c1.8 (2.0, 5.9)0.9 (0.5, 2.9)< 0.001
GCA (ng/ml)6160 (3476, 9978) b, c3044 (1274, 5920)d820 (428, 1824)< 0.001
GCDCA (ng/ml)11,440 (7800, 18,600)b, c5680 (3474, 10,960)d2527 (1768, 3980)< 0.001
TCA (ng/ml)7936 (4740, 12,245)c6080 (4080, 10,170)d574 (249, 1684)< 0.001
TCDCA (ng/ml)16,160 (8720, 23,908)c13,680 (8740, 19,600)d1633 (784, 3892)< 0.001
GCDCA/CDCA685 (394, 1288)b,c266 (100, 596)d13 (6, 20)< 0.001
  1. Data are presented as median (IQR)
  2. a P value: data were analyzed using Kruskal-Wallis test
  3. b Paired comparisons with significance (p < 0.017), using Mann-Whitney test between BA vs Non-BA
  4. c Paired comparisons with significance (p < 0.017), using Mann-Whitney test between BA vs Control
  5. d Paired comparisons with significance (p < 0.017), using Mann-Whitney test between Non-BA vs Control
  6. CA Cholic acid; CDCA Chenodeoxycholic acid; GDCA Glycodeoxycholic acid; GCA Glycocholic acid; GCDCA Glycochenodeoxycholic acid; TCA Taurocholic acid; TCDCA taurochenodeoxycholic acid