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Table 4 Number of acute rejection episodes in relation to the different gene polymorphisms

From: CYP and SXR gene polymorphisms influence in opposite ways acute rejection rate in pediatric patients with renal transplant

GENE polymorphism N° of acute rejection episodes
CYP3A5 AG (n = 12) (24.4%) 5* (41.6%)
GG (n = 37) (75.5%) 3 (1.0%)
CYP3A4B AA (n = 43) (87.7%) 7 (16.2%)
AG (n = 6) (12.2%) 1 (16.6%)
SXR A7635G AA (n = 16) (32.6%) 2 (12.5%)
AG (n = 24) (48.9%) 6 (25.0%)
GG (n = 9) (18.3%) 0* (0.0%)
SXR RS rs3842689 In/in (n = 19) (38.7%) 3 (12.9%)
In/del (n = 22) (44.8%) 4 (18.1%)
Del/del (n = 8) (16.32%) 1 (12.5%)
ABCB1 C1236T CC (n = 18) (36.7%) 3 (16.6%)
CT (n = 19) (38.7%) 2 (10.5%)
TT (n = 12) (24.4%) 3 (0.25%)
ABCB1 G2677T/A GG (n = 16) (32.6%) 2 (12.5%)
GT/A (n = 26) (53.0%) 5 (19.2%)
TT (n = 7) (14.2%) 1 (14.2%)
ABCB1 C3435T CC (n = 15) (30.6%) 4 (26.6%)
CT (n = 24) (48.9%) 2 (8.3%)
TT (n = 10) (20.4%) 2 (20.0%)
  1. * p-value < 0.05 at Fisher exact test