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Table 2 Comparison between groups

From: Influence of time under mechanical ventilation on bronchopulmonary dysplasia severity in extremely preterm infants: a pilot study

 

Mild BPD

Moderate/severe BPD

p

Maternal and gestational characteristics

 Tobacco use, yes (%)

2 (8)

4 (14,3)

0,672

 Chorioamnionitis, yes (%)

3 (12)

5 (18,5)

0,705

 Antenatal corticosteroids, yes (%)

23 (92)

20 (74,1)

0,143

Perinatal variables

 Intubation in the delivery room, yes (%)

12 (48)

20 (71,4)

0,072

 CPAP in the delivery room, yes (%)

13 (52)

8 (28,6)

0,99

Outcomes during hospitalization

 Time under MV (days)

19 [7,25–38]

43 [33,25-52,75]

< 0,001*

 CPAP before intubation, yes (%)

12 (56)

7 (25)

0,043*

 RDS, yes (%)

13 (76)

24 (85,7)

0,488

 Surfactant use, yes (%)

18 (72)

24 (85,7)

0,313

 Pulmonary hypertension, yes (%)

3 (12)

12 (42,9)

0,016*

 Pneumonia, yes (%)

23 (92)

28 (100)

0,218

 ROP classification, n (%)

  0

13 (52)

4 (14,3)

0,009

  1

6 (16)

11 (39,3)

0,23

  2

4 (16,2)

2 (7,1)

0,31

  3

2 (8)

11 (39,3)

0,003a

 Corrective surgery for ROP, yes (%)

1 (5,6)

4 (15,4)

0,634

 PDA, sim (%)

22 (88)

24 (85,7)

1

 Drug treatment for PDA, yes (%)

9 (40,9)

11 (45,8)

0,774

 Surgery for PCA, yes (%)

2 (6,5)

1 (4,2)

0,6

 NEC, yes (%)

3 (12)

3 (10,7)

1

 Surgery for NEC, yes (%)

1 (33,3)

2 (66,7)

1

 Sepsis, yes (%)

22 (88)

26 (92,9)

0,658

 VAD, yes (%)

5 (20)

2 (7,1)

0,234

Variables at discharge

 Lenght of stay (days)

81,5 [69,5-90,5]

109 [99–118,25]

< 0,001*

 GA at discharge (weeks)

38 [36,25-38,75]

41 [39–42,75]

< 0,001*

 Weight at discharge (g)

2031 [1868–2328]

2620 [2045–3030]

< 0,001*

 O2 discharge/transference, yes (%)

0 (0)

4 (14,3)

0,115

  1. GA gestational age, g grams, Apgar 5′ Apgar score at fifth minute of life, M male, MV mechanical ventilation, CPAP continuous positive airway pressure, RDS respiratory distress syndrome, ROP retinopathy of prematurity, PDA patente ductus arteriosus, NEC necrotizing enterocolits, VAD vasoactive drugs, O2 oxygen; * p < 0,05; ap < 0,006