Skip to main content

Table 1 Demographic and clinical characteristics of the SGA and AGA groups

From: Small for gestational age is a risk factor for thyroid dysfunction in preterm newborns

 SGAAGAP-value
Demographic factors
 Participants, n189661 
 Male sex111 (58.73)389 (58.85)0.976
 BW, kg1.56 ± 0.37*2.07 ± 0.51*< 0.001
1.58 (0.61 ~ 2.30)**2.10 (0.86 ~ 5.07)** 
  ELBW#1 (< 1 kg)12 (6.35)5 (0.76) 
  VLBW#2 (1 ~ 1.5 kg)68 (35.90)96 (14.55) 
  LBW#3 (> 1.5 kg ~ 2.5 kg)109 (57.67)447 (67.73) 
  NBW#4 (> 2.5 kg)0112 (16.97) 
GA, wk. (week)34.03 ± 2.05*33.53 ± 2.39*0.009
35 (28 ~ 36.86)**34.00 (26 ~ 36.86)** 
  Extremely preterm (< 28wk)2 (1.06)19 (2.87) 
  Early preterm (28 ~ 316/7wk)26 (13.76)134 (20.27) 
  Mild preterm (32 ~ 366/7wk)153 (85.19)508 (76.85) 
Z-score−1.85 ± 0.59−0.14 ± 0.72< 0.001
Ponderal index2.29 ± 0.422.46 ± 0.27< 0.001
Being a twin59 (31.22)154 (23.30)0.027
Caesarean section58 (30.69)307 (46.59)< 0.001
In vitro fertilization20 (10.58)83 (12.59)0.455
Clinical factors
 Low Apgar score at 1 min(< 7)30 (16.39)52 (8.01)0.001
 Low Apgar score at 5 min(< 7)13 (6.91)45 (6.85)0.975
 Respiratory distress syndrome65 (34.39)239 (36.16)0.655
 Severe IVH## (grade 3 or 4)4 (2.14)19 (2.89)0.577
 Necrotizing Enterocolitis13 (6.91)36 (5.46)0.452
 Cardiac problems35 (18.62)101 (15.40)0.290
Respiratory support
 Invasive33 (17.46)88 (13.31)0.150
 Noninvasive60 (31.75)195 (29.50)0.553
Surfactant administration50 (26.46)197 (29.80)0.371
Medications
 Steroids5 (2.64)13 (1.97)0.560
 Dopamine12 (6.35)26 (3.93)0.150
 Furosemide2 (1.05)5 (0.76)0.686
  1. #1-4ELBW Extremely low birth weight; VLBW Very low birth weight; LBW Low birth weight; NBW Normal birth weight
  2. * Presented as mean ± standard deviation
  3. ** Presented as median (range)
  4. ##IVH Intraventricular hemorrhage