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Table 3 Fungal colonization, systemic fungal infection, and mortality

From: Oral nystatin prophylaxis to prevent systemic fungal infection in very low birth weight preterm infants: a randomized controlled trial

Variable

Nystatin Group

(n = 47)

Control Group (n = 48)

RR

(95% CI)

p-value

Fungal colonization, n (%)

14 (29.8)

27 (56.3)

0.56

(0.36–0.90)

0.009

Colonization site(s)

 Single site colonization, n (%)

11 (23.4)

12 (25.0)

0.78 (0.49–1.26)

0.281

 Multiple sites colonization, n (%)

3 (6.4)

15 (31.3)

0.55 (0.37–0.72)

0.001

Colonization grade

 Light colonization, n (%)

5 (10.6)

7 (14.6)

reference

 

 Moderate colonization, n (%)

3 (6.4)

5 (10.4)

0.93 (0.46–1.92)

1.000

 Heavy colonization, n (%)

6 (12.8)

15 (31.3)

0.82 (0.47–1.42)

0.471

Systemic Fungal Infection, n (%)

0 (0)

5 (10.4)

0.09 (0.01–1.63)

0.056

 Prior colonization, n/total

4/5

 

0.130

 Multiple site colonization, n/total

2/5

 

0.053

Mortality

 Overall mortality, n (%)

7 (14.9)

9 (18.8)

0.86 (0.48–1.57)

0.616

 Fungal-related mortality, n (%)

0

0