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Table 3 Fungal colonization, systemic fungal infection, and mortality

From: Oral nystatin prophylaxis to prevent systemic fungal infection in very low birth weight preterm infants: a randomized controlled trial

Variable Nystatin Group
(n = 47)
Control Group (n = 48) RR
(95% CI)
p-value
Fungal colonization, n (%) 14 (29.8) 27 (56.3) 0.56
(0.36–0.90)
0.009
Colonization site(s)
 Single site colonization, n (%) 11 (23.4) 12 (25.0) 0.78 (0.49–1.26) 0.281
 Multiple sites colonization, n (%) 3 (6.4) 15 (31.3) 0.55 (0.37–0.72) 0.001
Colonization grade
 Light colonization, n (%) 5 (10.6) 7 (14.6) reference  
 Moderate colonization, n (%) 3 (6.4) 5 (10.4) 0.93 (0.46–1.92) 1.000
 Heavy colonization, n (%) 6 (12.8) 15 (31.3) 0.82 (0.47–1.42) 0.471
Systemic Fungal Infection, n (%) 0 (0) 5 (10.4) 0.09 (0.01–1.63) 0.056
 Prior colonization, n/total 4/5   0.130
 Multiple site colonization, n/total 2/5   0.053
Mortality
 Overall mortality, n (%) 7 (14.9) 9 (18.8) 0.86 (0.48–1.57) 0.616
 Fungal-related mortality, n (%) 0 0