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Table 1 Patients characteristics

From: Impact of rapid enterovirus polymerase chain reaction testing on management of febrile young infants < 90 days of age with aseptic meningitis

 Tested group Untested group 
CSF EV PCR +CSF EV PCR - p-value1
Patients, n422858 
Age in days, median (IQR)35
(17–48)
39
(33–64)
38
(23–58)
0.133
Gender male, n (%)24 (57.1%)15 (53.6%)34 (58.6%)0.906
Blood WBC, G/l, median (IQR)8.9
(7.5–11.2)
8.5
(6.6–11)
10.5
(7.8–13.3)
0.107
CRP, mg/l, median (IQR)4
(4–13)
6
(4–22)
4
(4–11)
0.344
CSF WBC, cells/μl, median (IQR)127
(32–496)
17
(10–60)
18
(8–63)
< 0.0112
 Mononuclear in %, median (IQR)80.1
(58.1–94)
85
(59.7–94)
87.1
(75–100)
0.0493
CSF protein, g/l, median (IQR)0.69
(0.55–0.94)
0.65
(0.43–0.92)
0.58
(0.42 -0.71)
0.0313
CSF glucose, mmol/l, median (IQR)2.7
(2.5–2.9)
2.8
(2.7–3.1)
2.8 (2.5–2.9)0.559
Contamination rate overall, n (%)410 (23.8%)10 (35.7%)23 (39.7%)0.245
  1. Abbreviations: CSF cerebrospinal fluid, EV enterovirus, WBC white blood cells, CRP C-reactive protein, IQR interquartile range;
  2. 1 Pearson Chi-squared test for categorical data, Kruskal-Wallis test for continuous data
  3. 2 Statistically significant difference between CSF EV PCR + and – patients (p < 0.001) and between CSF EV PCR + and untested group patients (p = 0.011)
  4. 3 Statistically significant difference between CSF EV PCR + and untested group patients
  5. 4 Contamination defined as non-relevant bacterial growth in culture from blood, CSF and/or urine