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Table 2 clinical features of six children with FS

From: Phenotypic variability in a child with Felty’s syndrome: a case report

Clinical featuresCase 1Case 2Case 3Case 4Case 5Case 6
Age at onset of JIA(Y)10.04.04.014.015.08.0
GenderFFFFFF
JIA subtypePolyarticularPolyarticularPolyarticularSystemicPolyarticularPolyarticular
Duration of JIA until FS(Y)5.811.04.510.02.04.0
SplenomegalyYesYesYesYesYesYes
HepatomegalyNoNoNoYesYesYes
Hemoglobin(g/l)Normal135.0122.0128.080.0118.0
Platelet count (×109/l)Not reported313.072.0105.0159.095.0
Leucocyte count (×109/l)1.84.12.82.74.16.2
Granulocyte count (× 109/l)0.51.71.31.53.13.92
RF (IU/l)1:480 PositiveNegativeNegativeNegativeNegative10,200.0 Positive
Anti-CCP(U/l)Not reportedNot reportedNot reportedNot reportedNegative384.0
Levels of complementNormalNANormalNANormalNormal
ANA1:120 Positive1:320 PositiveNegativeNegativeNegative1:320 Positive
Bone marrow findingsNormalNormalNormalNormalNormalNormal
MedicationsMTX, IbuprofenGold, HCQ, ASATolmetin, ASAPrednisolone, HCQ,
Ibuprofen, MTX
MTX, HCQ, MPPrednisolone, Diclofenac,
HCQ, Sulfasalazine, MTX,
Etanercept, Rituximab
Reference[4][5][6][7][8]*
  1. MTX Methotrexate, HCQ Hydroxychloroquine, ASA Acetylsalicylic acid, MP Methylprednisolone; *, our patient