Table 1 Clinical and laboratory characteristics of PANDAS and controls
PANDAS (n = 30) | Controls (n = 30) | p value | |
|---|---|---|---|
Age | 9 ± 3 | 9 ± 3 | 0.949 |
Gender (male/female) | 24/6 | 24/6 | 1 |
Glycaemia (mg/dL) | 83 ± 3.75 | 87 ± 3 | 0.617 |
Systolic blood pressure (mmHg) | 101 ± 3.79 | 112 ± 3 | 0.198 |
Diastolic blood pressure (mmHg) | 67 ± 2.55 | 70 ± 2 | 0.6 |
BMI | 18 ± 2 | 17 ± 1 | 0.157 |
Tic disorders (presence/absence) | 25/5 | 0 | – |
OCD (presence/ absence) | 10/20 | 0 | – |
Anti-streptolisinic title (UI/mL) | 409 ± 262 | 0 | – |
LPS (pg/ml) | 24.1 ± 9.2 | 8.1 ± 3.6 | < 0.001 |
sNOX2-dp (pg/ml) | 20.4 ± 8.1 | 16.3 ± 5.7 | 0.02 |
Zonulin (ng/ml) | 2.6 ± 1 | 1.7 ± 0.6 | 0.005 |
8-iso-PGF2α (pmol/L) | 175 ± 84 | 106 ± 43 | 0.001 |