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Table 1 Basic characteristics of participating mothers

From: Association of cleft lip and palate on mother-to-infant bonding: a cross-sectional study in the Japan Environment and Children’s Study (JECS)

maternal age

< 35

≥35

parity

primiparae

multiparae

primiparae

multiparae

Healthy

CL/P

Healthy

CL/P

Healthy

CL/P

Healthy

CL/P

(n = 25,628)

(n = 71)

(n = 31,693)

(n = 85)

(n = 6536)

(n = 18)

(n = 15,072)

(n = 37)

Age, Median (IQR)

28 (26, 31)

28 (25.7, 31)

30 (28, 32)

30 (27, 33)

37 (36, 39)

37.5 (36, 40)

37 (36, 39)

37 (35.5, 38)

MIBS score, Mean (SD)

2.23 (2.38)

1.75 (1.90)

1.74 (2.20)

2.02 (2.69)

2.21 (2.41)

2.14 (2.57)

1.74 (2.21)

3.08 (3.85)

Bonding disorders (≥5)

3528 (13.8)

5 (7.0)

3104 (9.8)

9 (10.6)

895 (13.7)

3 (16.7)

1503 (10.0)

9 (24.3)

K6 score, Mean (SD)

2.85 (3.63)

3.30 (4.24)

2.86 (3.75)

2.95 (4.15)

2.63 (3.34)

2.22 (2.71)

2.62 (3.39)

3.26 (4.57)

Depression (≥13)

715 (2.8)

2 (2.8)

955 (3.0)

3 (3.5)

128 (2.0)

0 (0)

299 (2.0)

3 (8.1)

Smoking habit, n (%)

 Never

15,988 (62.4)

41 (57.7)

17,665 (55.7)

50 (58.8)

3983 (61.0)

12 (66.7)

9153 (60.7)

24 (64.9)

 Stopped

8735 (34.1)

27 (38.0)

12,418 (39.2)

30 (35.3)

2379 (36.4)

6 (33.3)

5311 (35.2)

12 (32.4)

 Smoking

905 (3.5)

3 (4.2)

1610 (5.1)

5 (5.9)

174 (2.7)

0 (0)

608 (4.0)

1 (2.7)

Alcohol intake, n (%)

 Never

8332 (32.5)

26 (36.6)

11,906 (37.6)

31 (36.5)

2009 (30.7)

7 (38.9)

5200 (34.5)

15 (40.5)

 Stopped

15,373 (60.0)

42 (59.2)

16,643 (52.5)

43 (50.6)

3894 (59.6)

11 (61.1)

7719 (51.2)

20 (54.1)

 Drinking

1923 (7.5)

3 (4.2)

3144 (9.9)

11 (12.9)

633 (9.7)

0 (0)

2153 (14.3)

2 (5.4)

sex, n (%)

 Male

12,957 (50.6)

38 (53.5)

16,076 (50.7)

48 (56.5)

3359 (51.4)

11 (61.1)

7809 (51.8)

20 (54.1)

 Female

12,671 (49.4)

33 (46.5)

15,617 (49.3)

37 (43.5)

3177 (48.6)

7 (38.9)

7263 (48.2)

17 (45.9)

Feeding pattern, n (%)

 Breast

7442 (29.0)

5 (7.0)

11,932 (37.6)

17 (20.0)

1220 (18.7)

0 (0)

5346 (35.5)

5 (13.5)

 Mixed

17,670 (68.9)

53 (74.6)

19,008 (60.0)

62 (72.9)

5146 (78.7)

17 (94.4)

9344 (62.0)

26 (70.3)

 Formula

516 (2.0)

13 (18.3)

753 (2.4)

6 (7.1)

170 (2.7)

1 (5.6)

382 (2.5)

6 (16.2)