Table 1 Demographic and auxologic characteristics of participantsa
From: Factors associated with permanent hypothyroidism in infants with congenital hypothyroidism
Characteristic | All patients (n = 80) | Off trial success (n = 71) | Off trial failure (n = 9) | P | Early off trial (n = 9) | On-time off trial (n = 71) | P |
|---|---|---|---|---|---|---|---|
Male, n (%) | 40 (50.0) | 35 (49.3) | 5 (55.6) | 1 | 5 (55.6) | 35 (49.3) | 1 |
GA (weeks) | 33.6 ± 4.6 | 33.6 ± 4.5 | 34.0 ± 5.8 | 0.835 | 33.6 ± 4.5 | 33.7 ± 4.7 | 0.95 |
Age (treatment initiation, weeks) | 3.4 ± 3.1 | 3.2 ± 2.3 | 5.5 ± 6.8 | 0.349 | 3.0 ± 2.5 | 3.5 ± 3.2 | 0.687 |
Age (discontinuation trial, months) | 34.5 ± 4.6 | 34.6 ± 4.4 | 33.9 ± 5.9 | 0.67 | 23.7 ± 3.9 | 35.9 ± 2.2 | < 0.001 |
Wt (at birth, kg) | 2.1 ± 0.9 | 2.0 ± 0.9 | 2.3 ± 1.1 | 0.469 | 2.1 ± 0.8 | 2.1 ± 0.9 | 0.956 |
Wt (at treatment initiation) | 2.5 ± 1.0 | 2.4 ± 1.0 | 3.1 ± 1.3 | 0.094 | 2.3 ± 0.9 | 2.5 ± 1.0 | 0.518 |
Wt (at discontinuation) | 12.8 ± 1.8 | 12.8 ± 1.8 | 13.4 ± 1.8 | 0.287 | 11.7 ± 1.6 | 13.0 ± 1.8 | 0.047 |