Table 1 Baseline characteristics by treatment allocation
Characteristics | n | Total | HS1d n = 59 | HS3d n = 57 | p-value |
|---|---|---|---|---|---|
Gender (male n, %) | 116 | 76 (65.5) | 34 (57.3) | 42 (73.7) | 0.069 |
Age in month (mean ± SD) | 116 | 4.2 ± 2.4 | 4.1 ± 2.5 | 4.4 ± 2.4 | 0.427 |
Gestational age in weeks (mean ± SD) | 107 | 38.8 ± 4.0 | 38.4 ± 5.5 | 39.1 ± 1.4 | 0.378 |
Birthweight in g (mean ± SD) | 116 | 3340 ± 475 | 3299 ± 474 | 3382 ± 477 | 0.357 |
Weight in g (mean ± SD) | 110 | 6452 ± 1509 | 6290 ± 1456 | 6619 ± 1558 | 0.24 |
Environmental smoke exposure (n, %) | 116 | ||||
Current | 32 (27.6) | 17 (28.8) | (26.3) | 0.763 | |
During pregnancy | 18 (15.5) | 9 (15.2) | 9 (15.8) | 0.916 | |
Personal history of atopy (n, %) | 116 | 13 (11.2) | 4 (6.8) | 9 (15.7) | 0.124 |
Familial history of atopy (n, %) | 116 | 70 (60.3) | 33 (55.9) | 37 (64.9) | 0.323 |
Previous episode of bronchiolitis (n, %) | 116 | 14 (12.1) | 6 (10.2) | 8 (14) | 0.523 |
CSS at randomization (mean ± SD) | 116 | 5.7 ± 1.8 | 5.8 ± 1.7 | 5.5 ± 1.8 | 0.403 |
Associated treatments at admission (n, %) | 116 | ||||
Inhaled beta2agonists | 14 (12.1) | 9 (15.2) | 5 (8.8) | 0.284 | |
Antibiotics | 33 (28.4) | 17 (28.8) | 16 (28.1) | 0.929 | |
Paracetamol | 50 (43.1) | 37 (45.8) | 23 (40.3) | 0.556 |