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Table 5 Changes of blood inflammatory indicators and oxidative stress indicators before and after treatment in the conventional group and HP group (x ± s)

From: Changes of inflammatory mediators and oxidative stress indicators in children with Henoch-Schönlein purpura and clinical effects of hemoperfusion in the treatment of severe Henoch-Schönlein purpura with gastrointestinal involvement in children

 

Conventional group(30)

HP group(n = 30)

P value

 

d0

d4

d0

d4

 

IL-6(pg/mL)

18.23 ± 1.99

10.19 ± 1.56a

18.45 ± 1.62

7.60 ± 1.15bc

0.000

TNF-α(pg/mL)

17.24 ± 2.08

10.32 ± 1.35a

17.60 ± 2.77

9.48 ± 0.97bc

0.008

MDA(nmol/mL)

2.95 ± 0.19

2.26 ± 0.16a

2.97 ± 0.19

2.15 ± 0.18bc

0.015

SOD(U/mL)

38.44 ± 2.05

42.71 ± 1.98a

38.71 ± 2.26

45.74 ± 2.47bc

0.000

T-AOC(U/mL)

6.24 ± 0.54

8.51 ± 0.80a

6.20 ± 0.72

9.42 ± 0.71bc

0.000

  1. Note: a indicates comparison with the conventional group (d0), P = 0.000. b indicates comparison with HP group (d0), P = 0.000. c indicates comparison with the conventional group (d4), P < 0.047