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Table 2 IFX concentration by age group

From: Infliximab for pediatric patients with ulcerative colitis: a phase 3, open-label, uncontrolled, multicenter trial in Japan

 

6 to < 12 years

12 to 17 years

μg/mL, median (IQR)

n

μg/mL, median (IQR)

n

1 h after administration at Week 0

92.87 (76.62, 107.71)

4

97.17 (91.53, 107.43)

17

Week 8

20.65 (12.00, 23.08)

3

28.34 (20.39, 35.03)

16

Week 14

0.85 (0.26, 3.45)

3a

3.11 (0.80, 6.06)

15a

Week 22

0.34 (0.33, 0.57)

3a

2.65 (0.48, 5.21)

12a

Week 30

1.20 (0.00, 1.48)

3a

2.62 (0.00, 5.78)

11a

  1. aWeek 8 CAI-based responders
  2. CAI Clinical activity index, IFX Infliximab