Table 1 Demographics and baseline characteristics (full analysis set)
Characteristic | Number (%) or median (IQR) (total n = 21) |
|---|---|
Sex | |
Male, n (%) | 11 (52.4) |
Female, n (%) | 10 (47.6) |
Age (years), median (IQR) | 14.0 (12.0, 15.0) |
6 to < 12 years, n (%) | 4 (19.0) |
12 to 17 years, n (%) | 17 (81.0) |
Weight (kg), median (IQR) | 45.40 (40.00, 54.50) |
Height (cm), median (IQR) | 158.0 (150.0, 162.0) |
BMI (kg/m2), median (IQR) | 17.78 (15.71, 19.55) |
Disease duration (years), median (IQR) | 2.10 (1.10, 2.80) |
Extent of disease | |
Limited to left side of colon, n (%) | 1 (4.8) |
Extensive, n (%) | 20 (95.2) |
Concomitant medications, at baseline | |
Corticosteroids (oral), n (%) | 12 (57.1) |
Aminosalicylates, n (%) | 19 (90.5) |
5-aminosalicylates, n (%) | 17 (81.0) |
Sulfasalazine, n (%) | 3 (14.3) |
6-mercaptopurine/azathioprine, n (%) | 9 (42.9) |
Corticosteroid-refractory disease, n (%) | 3 (14.3) |
Corticosteroid-dependent disease, n (%) | 16 (76.2) |
CAI score, median (IQR) | 9.0 (8.0, 11.0) |
Partial Mayo score, median (IQR) | 6.0 (5.0, 7.0) |
Mayo score,a median (IQR) | 7.0 (5.0, 8.5) |
PUCAI score, median (IQR) | 45.0 (40.0, 60.0) |
CRP (mg/dL), median (IQR) | 0.20 (0.00, 0.60) |
TNF-α (pg/mL), median (IQR)b | 1.020 (0.000, 1.640) |