Table 1 Clinical characteristics of human metapneumovirus infection in hospitalized children
Characterístic | HMPV positive group (n = 22) | HMPV negative group (n = 398) | Total (n = 420) | P-value across groups |
|---|---|---|---|---|
Age (months) | Median: 43 (IQR 9–101) | Median: 21 (IQR 6–57) | Median: 21 (IQR: 7–60) | 0.08 |
Sex | 0.51 | |||
Male | 12 (54.6%) | 225 (56.5%) | 237 (56.4%) | |
Female | 10 (45.4%) | 173 (43.5%) | 183 (43.6%) | |
Comorbidities | ||||
Kidney disease | 4 (18.2%) | 36 (9%) | 40 (9.5%) | 0.15 |
Liver disease | 3 (13.6%) | 50 (12.6%) | 53 (12.6%) | 0.75 |
Heart disease | 1 (4.5%) | 67 (16.8%) | 68 (16.2%) | 0.23 |
Transplant | 2 (9.1%) | 45 (11.3%) | 47 (11.2%) | 1.0 |
Prematurity | 3 (13.6%) | 52 (13.1%) | 55 (13.1%) | 1.0 |
Bronchopulmonary dysplasia | 2 (9.1%) | 50 (12.6%) | 52 (12.4%) | 0.86 |
Metabolic diseases | 1 (4.5%) | 26 (6.5%) | 27 (6.4%) | 1.0 |
Primary immunodeficiency | 1 (4.5%) | 39 (9.8%) | 40 (9.5%) | 0.84 |
Cancer | 4 (18.2%) | 46 (11.6%) | 50 (11.9%) | 0.32 |
Any comorbidity | 15 (68.2%) | 237 (59.5%) | 252 (60%) | 0.28 |
Nutritional status | 0.97 | |||
Severe malnutrition | 4 (18.2%) | 65 (13.3%) | 69 (16.4%) | |
Malnutrition | 4 (18.2%) | 78 (19.6%) | 82 (19.5%) | |
Normal | 13 (59.1%) | 244 (61.3%) | 257 (61.2%) | |
Overweight | 1 (4.5%) | 10 (2.7%) | 11 (2.6%) | |
Obesity | 0 (0%) | 1 (0.3%) | 1 (0.3%) | |
Diagnoses | 0.75 | |||
Croup | 0 (0%) | 7 (1.8%) | 7 (1.7%) | |
Bronchiolitis | 3 (13.6%) | 74 (18.6%) | 77 (18.3%) | |
Pneumonia | 10 (45.5%) | 200 (50.3%) | 210 (50%) | |
Asthma attack | 0 (0%) | 18 (4.5%) | 18 (4.3%) | |
Recurrent wheezing | 2 (9.1%) | 14 (3.5%) | 16 (3.8%) | |
Laryngitis | 0 (0%) | 4 (1%) | 4 (0.9%) | |
ARDS | 3 (13.6%) | 24 (6%) | 27 (6.4%) | |
Rhinopharyngitis | 4 (18.2%) | 55 (13.8%) | 59 (14.1%) | |
Sinusitis | 0 (0%) | 1 (0.3%) | 1 (0.3%) | |
Tracheitis | 0 (0%) | 1 (0.3%) | 1 (0.3%) | |
Type of infection | 0.43 | |||
HAI | 5 (22.7%) | 122 (30.6%) | 127 (30.2%) | |
Community | 17 (77.3%) | 276 (69.4%) | 293 (69.8%) | |
Bacterial coinfection | 6 (27.3%) | 151 (38%) | 157 (37.4%) | 0.31 |
Antibiotics | 0.5 | |||
Yes | 17 (77.3%) | 281 (70.6%) | 298 (71%) | |
No | 5 (22.7%) | 117 (29.4%) | 122 (29%) | |
Viral coinfection | 5 (22.7%) | 56 (14%) | 61 (14.5%) | 0.03 |
Length of hospital stay | Median: 10.5 days (IQR 6–26) | Median: 12 days (IQR 6–27) | Median: 12 days (IQR: 6–27) | 0.42 |