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Table 2 Clinical outcomes of infants with initial and delayed thyroid-stimulating hormone elevations and control

From: Initial and delayed thyroid-stimulating hormone elevation in extremely low-birth-weight infants

Outcome

Initial TSH Elevation (N = 5)

Delayed TSH Elevation (N = 42)

Control (N = 251)

Mortality

2 (40) *

2 (5)

9 (4)

BPD (≥ moderate)

2/3 (67)

22/40 (55)

95/250 (38)

IVH (≥ 3)

1 (20)

7 (17)

13 (5)

PVL

1 (20)

3 (7)

15 (6)

NEC (≥ Stage 2b)

0 (0)

2 (5)

18 (7)

ROP requiring laser treatment

1/4 (25)

20 (48)

42/250 (17)

Composite morbidity

4 (80)

35 (83)

131 (52)

  1. Values are presented as n (%). Values are adjusted by gestational age, birth weight, Apgar score at 5 min and antenatal steroid use
  2. BPD bronchopulmonary dysplasia, IVH intraventricular hemorrhage, PVL periventricular leukomalacia, NEC necrotizing enterocolitis, ROP retinopathy of prematurity
  3. * P < 0.05, vs Control