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Table 2 Clinical outcomes of infants with initial and delayed thyroid-stimulating hormone elevations and control

From: Initial and delayed thyroid-stimulating hormone elevation in extremely low-birth-weight infants

Outcome Initial TSH Elevation (N = 5) Delayed TSH Elevation (N = 42) Control (N = 251)
Mortality 2 (40) * 2 (5) 9 (4)
BPD (≥ moderate) 2/3 (67) 22/40 (55) 95/250 (38)
IVH (≥ 3) 1 (20) 7 (17) 13 (5)
PVL 1 (20) 3 (7) 15 (6)
NEC (≥ Stage 2b) 0 (0) 2 (5) 18 (7)
ROP requiring laser treatment 1/4 (25) 20 (48) 42/250 (17)
Composite morbidity 4 (80) 35 (83) 131 (52)
  1. Values are presented as n (%). Values are adjusted by gestational age, birth weight, Apgar score at 5 min and antenatal steroid use
  2. BPD bronchopulmonary dysplasia, IVH intraventricular hemorrhage, PVL periventricular leukomalacia, NEC necrotizing enterocolitis, ROP retinopathy of prematurity
  3. * P < 0.05, vs Control