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Table 1 Clinical predictor variables

From: Early prediction of spontaneous Patent Ductus Arteriosus (PDA) closure and PDA-associated outcomes: a prospective cohort investigation

Patient Demographics Antenatal Risk Factors Early Postnatal Illness Severity Diagnoses in Early Postnatal Perioda Medications (by date, doseb, route) Physiologic Measures (date)
Birth GA
Birth weight z-score for GA
Sex
Race/Ethnicity
Transported from outside birth hospital
Singleton or multiple gestation
Social status (BSMSS)
Maternal corticosteroid administration
Maternal magnesium sulfate administration
Pre-eclampsia
Clinical and histological chorioamnionitis
Apgar scores
Score for Neonatal Acute Physiology (SNAPPE-II) variables [72]
Variables from NRN Extremely Preterm Outcomes Prediction Tool [73, 74]
IVH Grade 3 or 4 (only included in models after routine ultrasound at 7 postnatal days)
Necrotizing enterocolitis
Pneumothorax
Spontaneous intestinal perforation
Seizure
Indomethacin
Caffeine
Diuretics
Inhaled corticosteroids
Surfactant treatment
Vitamin A
Total daily fluid intakeb
Daily respiratory support modality
Mean daily FiO2
Oxygen saturation index
Mean arterial blood pressureb
Daily urine outputb
  1. a Will only include diagnoses in models that were present prior to model specific week during postnatal weeks 1 to 4
  2. b Will weight adjust by kg
  3. GA gestational age, BSMSS Barratt Simplified Measure of Social Status, IVH intraventricular hemorrhage