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Table 2 Comparison between singletons and multiples regarding cardiometabolic indicators at 7 years follow-up evaluation

From: Different levels of cardiometabolic indicators in multiple vs. singleton children

 

Crude value

p

Age and sex z-scoreb

p

Singletons

Multiples

Singletons

Multiples

Cardiometabolic characteristics at age 7a

 Weight (kg)

26.2 (26.1, 26.4)

24.0 (23.1, 25.0)

< 0.001

0.02 (−0.01; 0.04)

− 0.41 (− 0.59; − 0.24)

< 0.001

 Height (cm)

123.6 (123.4, 123.7)

121.3 (120.3, 122.2)

< 0.001

− 0.01 (− 0.04; 0.02)

− 0.45 (− 0.62; − 0.28)

< 0.001

 Body mass index (kg/m2)

17.1 (17.0, 17.1)

16.3 (15.8, 16.7)

< 0.001

0.73 (0.70; 0.76)

0.27 (0.07; 0.48)

< 0.001

 Fat mass index (kg/m2)

3.0 (2.9, 3.1)

2.3 (1.9, 2.7)

0.001

−0.07 (− 0.10; − 0.04)

−0.39 (− 0.57; − 0.21)

0.001

 Fat-free mass index (kg/m2)

14.0 (14.0, 14.1)

13.9 (13.7, 14.2)

0.360

0.09 (0.07; 0.12)

0.01 (− 0.16; 0.18)

0.325

 Waist circumference (cm)

59.1 (59.0, 59.3)

56.6 (55.4, 57.8)

< 0.001

−0.03 (− 0.06; − 0.01)

−0.40 (− 0.57; − 0.23)

< 0.001

 Waist-to-height ratio

0.48 (0.48, 0.48)

0.47 (0.46, 0.48)

0.023

−0.05 (− 0.07; − 0.03)

−0.20 (− 0.34; − 0.06)

0.044

 Glucose (mg/dL)

82.4 (82.2, 82.7)

82.4 (80.7, 84.1)

0.980

−0.09 (− 0.13; − 0.05)

− 0.11 (− 0.40; 0.19)

0.909

 Insulin (μIU/mL)

5.2 (5.0, 5.3)

4.5 (3.8, 5.2)

0.061

0.01 (− 0.03; 0.04)

− 0.20 (− 0.43; 0.03)

0.082

 HDL-cholesterol (mg/dL)

56.3 (55.9, 56.7)

58.0 (55.4, 60.6)

0.201

0.08 (0.04; 0.11)

0.22 (−0.01; 0.44)

0.218

 Triglycerides (mg/dL)

62.2 (61.3, 63.2)

60.9 (54.8, 67.1)

0.693

−0.05 (− 0.09; − 0.02)

−0.09 (− 0.29; 0.12)

0.745

 hs-C-reactive protein (mg/L)

1.31 (1.20, 1.43)

1.02 (0.43, 1.61)

0.346

0.00 (− 0.03; 0.04)

− 0.03 (− 0.28; 0.22)

0.816

 Systolic blood pressure (mmHg)

105.2 (105.0, 105.5)

103.4 (102.0, 104.9)

0.016

0.71 (0.68; 0.73)

0.70 (0.58; 0.83)

0.970

 Diastolic blood pressure (mmHg)

69.8 (69.7, 70.1)

68.1 (67.0, 69.4)

0.006

1.04 (1.02; 1.06)

0.97 (0.86; 1.07)

0.185

  1. a Mean values and 95% confidence intervals adjusted for non independence
  2. b For systolic and diastolic blood pressure - age, sex and height z-score