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Table 2 Urinary concentrations of phthalates and BPA in girls with CPP and control groups

From: The analysis of endocrine disruptors in patients with central precocious puberty

 

CPP (N = 47)

Pre-pubertal control (N = 26)

P value

CPP (N = 47)

Pubertal control (N = 21)

P value

MBzP (μg/g creatinine)

3.1 (1.8–4.9)

4.3 (3.3–11.1)

0.026

3.1 (1.8–4.9)

1.7 (0.64–4.6)

0.077

MECPP (μg/g creatinine)

29.3 (22.1–44.7)

53.7 (35.1–86.4)

< 0.001

29.3 (22.1–44.7)

28.7 (22.7–45.6)

0.733

MEHHP (μg/g creatinine)

18.0 (14.6–28.5)

35.7 (23.0–54.3)

0.001

18.0 (14.6–28.5)

21.4 (13.5–29.4)

0.762

MEOHP (μg/g creatinine)

15.4 (12.1–25.0)

29.1 (18.7–35.9)

< 0.001

15.4 (12.1–25.0)

12.1 (8.0–17.8)

0.405

MnBP (μg/g creatinine)

25.2 (10.9–151.0)

66.0 (39.4–106.1)

< 0.001

25.15 (10.92–150.98)

33.3 (25.2–46.2)

0.981

Bisphenol A (μg/g creatinine)

0.63 (0.4–1.1)

2.0 (0.93–3.5)

< 0.001

0.63 (0.4–1.1)

1.7 (1.1–3.3)

0.092

  1. Data are presented as median and interquartile range. MBzP monobenzyl phthalate, MECPP mono-2-ethyl-5-carboxypentyl phthalate, MEHHP mono-2-ethyl-5-hydroxyhexyl phthalate, MEOHP mono-2-ethyl-5-oxohexyl phthalate, MnBP mono-n-butyl phthalate