From: Mortality and severe morbidity of very preterm infants: comparison of two French cohort studies
OGP (n = 1272) | EPIPAGE 2 (n = 3669) | P values | |||
---|---|---|---|---|---|
n | % or mean ± SE | n | % or mean ± SE | ||
Obstetrical characteristics | |||||
Maternal age (years) | 1115 | 28.2 ± 0.2 | 3669 | 29.7 ± 0.1 | < 0.001 |
Maternal hypertension | 290 | 29.3 | 849 | 24.6 | 0.003 |
Maternal diabetes | 132 | 11.6 | 308 | 9.4 | 0.030 |
Premature prolonged rupture of membranes | 204 | 22.3 | 1336 | 36.3 | < 0.001 |
Antenatal steroid therapy | 1022 | 89.7 | 2989 | 83.4 | < 0.001 |
Multiple birth | 299 | 23.5 | 1202 | 32.7 | < 0.001 |
Caesarean delivery | 709 | 60.8 | 2346 | 65.8 | 0.002 |
Neonatal characteristics | |||||
Gestational age, weeks (WG) | 1272 | 28.6 ± 0.06 | 3669 | 28.5 ± 0.03 | 0.201 |
24–26 | 222 | 17.5 | 791 | 21.6 | 0.008 |
27–28 | 307 | 24.1 | 842 | 22.9 | |
29–31 | 743 | 58.4 | 2036 | 55.5 | |
Birthweight (grams) | 1271 | 1174.7 ± 9.6 | 3669 | 1194.2 ± 4.8 | 0.098 |
< 750 | 152 | 11.9 | 423 | 10.0 | 0.177 |
750–1000 | 290 | 22.8 | 875 | 22.0 | |
1000–1250 | 302 | 23.8 | 890 | 25.3 | |
≥ 1250 | 527 | 41.5 | 1481 | 42.7 | |
Small for gestational agea | 180 | 14.2 | 467 | 12.9 | 0.253 |
Male sex | 686 | 53.9 | 1933 | 52.7 | 0.446 |
Outborn status | 76 | 6.0 | 533 | 14.5 | < 0.001 |
Apgar score at 5 min < 7 | 69 | 7.4 | 646 | 18.0 | < 0.001 |
Surfactant therapy | 678 | 54.0 | 2427 | 65.1 | < 0.001 |