Skip to main content

Table 3 Twelve isolates were analyzed by WGS. The 12 isolates consisted of seven non-typeable isolates and five MDR defined isolates

From: Pneumococcal carriage among children under five in Accra, Ghana, five years after the introduction of pneumococcal conjugate vaccine

Isolate number MLST type (ST)a Clonal complex (CC)/ nearest ST Genotype/Capsular locus top hit (Nearest match) Serotype Pen/Tetra/SXT/Ery (Phenotypical) tet(M) ermB PBP 1a PBP 2b PBP 2x Predicted value*/Phenotype value
G10 (2–5–36-12-2-21-?) ST908/ST11041 Top hit: Genotype 38 NT I/S/R/S 38 25 43 MIC =? / MIC = 1
C131 (2–5–36-12-2-21-?) ST908/ST11041 Top hit: Genotype 38 NT I/S/R/S + (Tn916) 38 25 43 MIC =? / MIC = 2
C28 (2–5–36-12-2-21-?) ST908/ST11041 Top hit: Genotype 38 NT I/S/R/S + (Tn916) 38 25 43 MIC =? / MIC = 2
G11 344 Singleton Top hit: Genotype 38 NT I/R/R/S + (0)c 55 16 150 MIC =? / MIC = 0.12
C139 (2–149–1-12-6-494-14) ST11264 Top hit: Genotype 14 NT S/R/I/S + (Tn916) 24 73 192 MIC =? / Oxa sentitive
C140 9735 CC63 Top hit: Genotype 14 NT S/R/R/S + (Tn916) 24 73 192 MIC =?/Oxa sentitive
G7 (2–37–36-29-17-21-14) ST9735 Top hit: Genotype 14 NT I/R/R/S + (Tn916) 24 73 192 MIC =? / MIC = 0.12
D012 2613 Singleton Genotype 15A 15A I/R/S/R + (Tn916) + (0)c 34 89 147 MIC = 2/ MIC = 2
G14 320 CC320 Genotype 19A 19A I/R/R/R + (0)c + (0)c 13 11 16 MIC = 4/ MIC = 1
G27 320 CC320 Genotype 19A 19A I/R/R/R + (0)c 13 11 16 MIC = 4/ MIC = 1
G28 320 CC320 Genotype 19A 19A I/I/I/R + (0)c + (0)c 13 11 16 MIC = 4/ MIC = 1
C88 320 CC320 Genotype 19A 19A I/R/R/R + (0)c + (0)c 13 11 16 MIC = 4/ MIC = 1
  1. aThe MLST locus allele is presented as (aroE-gdh-gki-recP-spi-xpt-ddl)
  2. * Predicted level of resistance to penicillin according to CDC (https://www.cdc.gov/streplab/pneumococcus/mic.html)
  3. ? Predicted value is not presented (https://www.cdc.gov/streplab/pneumococcus/mic.html)