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Table 1 Characteristics of participating children

From: Pneumococcal carriage among children under five in Accra, Ghana, five years after the introduction of pneumococcal conjugate vaccine

  Total number of children Number of children with carriage of S. pneumoniae (%, 95 CI) OR (95% CI)*
(p-value)*
 
Overall carriage rate 410 220 (54, 49–59)   
Females carriage rate 200 108 (54, 47–61) 1  
Males carriage rate 210 112 (53, 47–60) 0.97 (0.66–1.44) (P = 0.892)  
Number of Children carrying PCV-13 serotypesa 410 81 (20, 16–24)   
Number of Children carrying non-PCV-13 serotypesa 410 153 (37, 33–42)   
  Median age (Month) Range (Month) Interquartile range (month)  
Children 36 (6–60) 36–48  
Males 36 (6–60) 36–48  
Females 36 (12–60) 36–48  
  Vaccination status of all participants Vaccination status of carriers   
PCV13 vaccinated 407 (99.3%) 220 (100%)   
Unknown 2 0   
Not vaccinated 1 0   
Age group (months) Total number of children Number of children with carriage of S. pneumoniae (%) (95% CI) OR (95% CI)*
(p-value)*
Number of children with multiple serotypes
0–11 2 1 (50, 13–200) 1 0
12–23 22 9 (40, 25–68) 0.69 (0.03–19.06) (P = 0.804) 0
24–35 73 41 (56, 46–69% 1.28 (0.05–33.24) (P = 0.863) 3
36–47 178 105 (59, 52–67%) 1.44 (0.05–36.76) (P = 0.798) 10
48–60 135 64 (47) (40–57%) 0.90 (0.03–23.11) (P = 0.942) 1
Total 410 220 (54) (49–59%)   14
  1. *Odds ratios, confidence intervals and p-values were calculated using a generalized linear model (glm function in R)
  2. a. Because 14 children were carrying two different serotypes, the number of children carrying the multiple serotupes in these two groups exceed 220 children and the figure is currently 234 cases