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Table 2 Estimation of Syphilis Treatment Associated Cost (Euros) for Babies Treated for Risk of Congenital Syphilis

From: Better care for babies: the added value of a modified reverse syphilis testing algorithm for the treatment of congenital syphilis in a maternity Hospital in Central African Republic

Cost Calculations (Euros)a
Scenario A: Assumes that all neonatal patients were treated for 10 days with penicillin (PCN) irrespective of maternal RPR results.
Syphilis treatment associated cost of hospital stay for each patient = (Cost of unit of PCN [3.07] × 23 doses) + (Cost of hospital day [10.27] × 10 days).
Scenario B: Assumes that all mothers were tested with both SD Bioline and RPR. Patients born to RPR reactive mothers were treated for 10 days with IV penicillin while patients born to RPR non-reactive mothers were treated with a single dose of penicillin.
RPR reactive: Syphilis treatment associated cost of hospital stay = (Cost of unit of PCN [3.07] × 23 doses) + (Cost of hospital day [10.27] × 10 days) + Cost of RPR test unit [0.72].
RPR non-reactive: Syphilis treatment associated cost of hospital stay = Cost of unit of PCN [3.07] + Cost of hospital day [10.27] + Cost of RPR test unit [0.72].
Actual situation:
Syphilis treatment associated cost of hospital stay for each patient = (Cost of unit of PCN [3.07] × # of doses of PCN) + (Cost of hospital day [10.27] × # of hospital days) + (Cost of RPR test unit [0.72]).
  1. PCN Penicillin, RPR Rapid plasma reagin
  2. Legend: aAll costs are in Euros. Estimated and actual costs at MSF Castors Maternity Hospital, March 2017 to February 2018