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Table 1 Reported cases in the literature of DVT, IVCA and atrophic kidney compatible with KILT-syndrome

From: Thrombophlebitis hiding under a KILT – case report on 40 years long-term follow-up of neonatal renal vein thrombosis

Author, year of publishing [Ref.]

Sex/ Age

Presentation

Affected kidney

Imaging

Laboratory workup

Therapy

Follow up duration, outcome

Glerup 1994 [25]

M/18

DVT

Right

Cavography, US

NH, TRO

AC

Not reported

Salgado 1998 [26]

M/49

Recurrent DVT, failure to advance catheter

Right

US, Venography, MRI, CT

TRO

AC

Not reported

Timmers 1999 [27]

M/37

DVT, mediastinal mass in chest X-ray, no precipitating factors

Right

US, Chest X-ray, CT, MRI

TRO

UFH, OAC, ES

No recurrence, time unknown

Tsuji 2001 [28]

M/21

DVT

Right

US, CT

TRO

UFH, Urokinase, Warfarin, Aspirin, ES

Not reported

Chee 2001 [10]

F/26

DVT, no precipitating factors

Left

US, CT

TRO

AC lifelong

22 months, no recurrence

Van Veen 2002 [13]

F/16

Bilateral DVT, no precipitating factors

Left

CT

NH

Not reported

Not reported

Gayer 2003 [17]

M/46

Recurrent unilateral DVT

Right

CT

Not reported

Not reported

Not reported

Iqbal 2008 [22]

M/54

Abdominal pain, swelling over right flank, DVT

Left

US, CT

Not reported

LMWH, warfarin

Not reported

Lawless 2012 [23]

M/50

intracranial hemorrhage, DVT, failure to advance catheter

Left

US, MRI

Not reported

Attempted IVC Filter; no AC due to hemorrhage

Not reported

Bami 2015 [20]

M/14

Left leg pain, DVT, no precipitating factors

Left

CT

NH

LMWH then switch to warfarin

Follow up by hematologists

Duicu 2016 [21]

M/12

Abdominal pain, acute thrombosis of renal vein, no precipitating factors

Right

CT; Follow up MRI

TRO

LMWH, warfarin plus antiplatelet, ES

2½ years, OAC, ES

 

F/12

Right lower extremity pain, DVT, no precipitating factors,

Left

Angio CT

TRO

LMWH, antiplatelet, higher dose LMWH alone, warfarin

3 months, OAC, ES

Fung 2017 [18]

M/41

Left loin pain, low grade fever, DVT

Left

US, CT

Not reported

LMWH

Follow up by hematologists, duration unknown

Singh 2017 [24]

F/28

Pelvic pain, menorrhagia

Left

US, CT

Not reported

Not reported

Not reported

Pomeranz 2018 [19]

F/11

Left leg pain, limping, low grade fever, DVT

Left

MR venogram

TRO

LMWH, switch to warfarin

3 months

Sagban 2015 [29]a

M:F/ 3.2:1

DVT (right sided RR 1.7; both sided RR 2.0)

a

US, CT or MRI plus veno-graphy in some cases

 

AC, when feasible combined with surgery

Not reported

  1. Abbreviations: DVT deep vein thrombosis, IVCA inferior vena cava atresia, AC anticoagulation, ES elastic stockings, f female, m male, NH normal hemostasis, OAC oral anticoagulant, RR relative risk, TRO thrombophilia ruled out, UFH unfractioned heparin, LMWH low molecular weight heparin, US ultrasound, CT computed tomography, MRI magnetic resonance imaging
  2. aAnalysis of 41 patients and literature review of 123 cases with IVCA: hypoplasia/aplasia of left and right kidney in 2.4 and 4.9%, respectively; no case specific details are given