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Table 2 Laboratory parameters in blood samples from patients with SCN1

From: Functional characteristics of circulating granulocytes in severe congenital neutropenia caused by ELANE mutations

Patient

Cells, ×  109/La

Haemoglobinb

CRPc

WBC

Neutrophils

Eosinophils

Monocytes

Thrombocytes

(g/L)

(mg/L)

P01

6.85 (5.4–7.9)

0.78 (0.32–1.12)

0.59 (0.52–0.75)

0.77 (0.54–1.26)

710 (653–761)

96 (91–98)

19.8 (12.0–33)

P02

8.71 (5.5–11.4)

0.80 (0.50–1.14)

0.38 (0.00–0.76)

0.91 (0.21–1.82)

770 (567–1011)

109 (100–127)

30.9 (4.7–147)

P03

6.16 (3.9–8.9)

1.04 (0.00–3.90)

0.39 (0.00–0.87)

1.81 (0.03–3.87)

404 (240–702)

106 (81–123)

40.0 (0.0–161)

P04

7.79 (5.5–18.8)

0.75 (0.00–10.77)

0.32 (0.00–0.61)

0.80 (0.12–1.53)

462 (209–785)

102 (84–115)

31.4 (0.0–96)

P05

8.10 (5.9–10.7)

1.01 (0.00–2.36)

0.35 (0–00-0.79)

1.94 (0.24–3.23)

398 (243–606)

108 (90–120)

58.1 (0.5–196)

P06

7.53 (5.2–9.8)

0.91 (0.00–2.18)

0.27 (0.00–0.67)

1.35 (0.32–2.73)

415 (257–589)

104 (88–124)

59.2 (0.8–178)

P07

7.38 (4.0–11.8)

0.60 (0.20–3.10)

0.35 (0.01–0.60)

2.07 (0.71–4.13)

375 (272–737)

105 (98–111)

73.8 (13.0–157)

P08

9.60 (7.1–11.2)

0.68 (0.00–1.35)

0.74 (0.00–1.40)

1.93 (1.80–2.01)

427 (282–597)

107 (105–112)

49.6 (33.0–66)

P09

7.60 (3.2–10.2)

1.01 (0.04–3.50)

0.39 (0.03–1.13)

1.54 (0.03–4.51)

357 (237–479)

105 (94–134)

29.1 (0.8–92)

  1. All values are the mean of > 30 measurements (range) for each patient
  2. aNormal range of cell counts × 109/L: White Blood cells (WBC; 4.5–15), Neutrophils (1.5–8.5), Eosinophils (0.04–0.4), Monocytes (0.1–1), and Thrombocytes (150–350) [20]
  3. bNormal range of haemoglobin: 110–160 g/L
  4. cNormal range of C-reactive protein (CRP): < 8 mg/L