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Table 1 The underlying condition and prior antibiotics use in the 66 patients with invasive S. pyogenes infection

From: A multi-center clinical investigation on invasive Streptococcus pyogenes infection in China, 2010–2017

Underlying condition

N

%

Previous antibiotics

N

%

Leukemia

2

3.0

Azithromycin, IV × 2–5 d

7

10.6

Varicella

2

3.0

Cephalosporins, Oral × 3–5 d

3

4.6

Skin burn

2

3.0

Azithromycin, Oral ×3 d

1

1.5

Skin hemangioma

2

3.0

Erythromycin, Oral ×3 d

1

1.5

Nephrotic syndrome

1

1.5

Piperacillin-tazobactam, IV × 1 d

1

1.5

Still’s disease

1

1.5

Erythromycin, IV × 1 d;

1

1.5

  

Clindamycin, IV × 1 d

  

Cerebral trauma

1

1.5

Azithromycin, IV × 5 d;

1

1.5

  

Clindamycin, IV × 1 d

  

Craniocerebral trauma

1

1.5

Meropenem + vancomycin +

1

1.5

  

Metronidazole, IV × 3 d

  

Cerebrospinal fluid rhinorrhea

1

1.5

Meropenem, IV × 3 d;

1

1.5

  

Lynezoliane, IV × 1 d

  

None

53

80.5

Piperacillin-tazobactam, IV × 1 d;

1

1.5

  

Clindamycin, IV × 4 d;

1

1.5

  

Vancomycin + Mezlocillin, IV × 1d

  
  

None

47

71.3

Total

66

100

Total

66

100

  1. Note: IV, intravenous