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Table 3 Course of Study Intervention

From: Evaluation of two SpO2 alarm strategies during automated FiO2 control in the NICU: a randomized crossover study

  Loose Alarm Strategy Tight Alarm Strategy P
Number of subjects 21 21
Automated FiO2 Settings
 High Target-Range (SpO2%) 95.1 (0.8) 95.0 (0.7) ns
 Low Target-Range (SpO2%) 88.4 (1.0) 88.5 (1.0) ns
 High SpO2 Alarm (SpO2%) 98.0 (0.9) 96.3 (0.8) < 0.001
 Low SpO2 Alarm (SpO2%) 85.6 (1.1) 87.4 (1.0) < 0.001
 SpO2 alarm delay (sec) 90.0 (2.9) 30.4 (1.7) < 0.001
Median FiO2 (%) 28.1 (6.2) 30.7 (8.6) ns
Median SpO2 (%) 92.5 (1.1) 92.1 (1.0) 0.039
SpO2 86–96%* (%time) 89.7(6.8) 91.5 (8.9) ns
Normoxemia** (%time) 95.2 (3.9) 94.9 (4.6) ns
Manual FiO2 adjustments (/day) 2 (1–5) 2 (2–3) ns
  1. * during periods when FiO2 > 0.21, **Normoxemia is defined as SpO2 between 86 and 96% or > 96% if FiO2 = 0.21. P for paired comparison of the mean (SD) or median (25th–75th percentile) with paired t test or Wilcoxon signed-rank test