|
Characteristic
|
Crude HR
|
95% CI
|
p value
|
Adjusted HR
|
95% CI
|
p value
|
|---|
|
Congenital anomaly
|
|
Yes
|
0.89
|
0.39–2.02
|
0.770
|
0.54
|
0.13–2.23
|
0.393
|
|
No (Ref)
|
|
Sex
|
|
Male
|
1.22
|
0.83–1.80
|
0.308
| | | |
|
Female (Ref)
|
|
Gestational age at birth (in weeks) ‡
|
0.87
|
0.82–0.92
|
< 0.0001a
|
0.86
|
0.81–0.91
|
< 0.0001*
|
|
Age at presentation (in days) ‡
|
0.93
|
0.88–0.99
|
0.015 a
|
1.05
|
0.97–1.13
|
0.199
|
|
Birth weight
|
|
<1.5 kg (Ref)
|
|
1.5–2.49 kg
|
1.04
|
0.48–2.28
|
0.913
| | | |
|
≥2.5
|
1.26
|
0.62–2.54
|
0.527
| | | |
|
Type of gestation
|
|
Singleton (Ref)
|
|
Multiple
|
0.54
|
0.26–1.10
|
0.090 a
|
0.73
|
0.31–1.72
|
0.476
|
|
Severe perinatal asphyxia
|
|
Yes
|
3.97
|
2.66–5.93
|
< 0.0001a
|
5.41
|
3.05–9.62
|
< 0.0001*
|
|
No (Ref)
|
|
Co-morbidity
|
|
Yes
|
1.40
|
0.89–2.20
|
0.150 a
|
1.18
|
0.63–2.19
|
0.603
|
|
No (Ref)
|
|
Maternal parity
|
|
1–2 (Ref)
|
|
3–4
|
0.87
|
0.53–1.42
|
0.575
| | | |
|
≥5
|
0.58
|
0.18–1.85
|
0.357
| | | |
|
Antenatal care
|
|
Yes (Ref)
|
|
No
|
0.57
|
0.23–1.41
|
0.222
| | | |
- *Statistically significant; ‡treated as a continuous variable
