Table 8 Association of VDR gene polymorphisms (FokI, TaqI, BsmI and ApaI) genotypes with three autoantibodies, ICA (islet cell autoantibody), GADA (glutamic acid decarboxylase) and INS (insulin autoantibody) in Kuwaiti T1DM patients
Genotype | ICA + ve* (%) | GADA + ve* (%) | INS + ve* (%) |
|---|---|---|---|
FokI | |||
 ff | 101/178 (57) | 146/178 (82) | 126/178 (71) |
 Ff | 16/30 (53) | 26/30 (87) | 21/30 (70) |
 FF | 25/45 (57) | 37/45 (82) | 30/45 (68) |
TaqI | |||
 CC | 35/61 (57) | 52/61 (85) | 43/61 (71) |
 TC | 53/96 (55) | 85/96 (89) | 70/96 (73) |
 TT | 54/96 (56) | 72/96 (75) | 64/96 (67) |
BsmI | |||
 bb | 19/29 (66) | 24/29 (83) | 23/29 (79) |
 Bb | 46/83 (55) | 72/83 (87) | 54/83 (65) |
 BB | 77/141 (55) | 113/141 (80) | 100/141 (71) |
ApaI** | |||
 GG | 14/29 (48) | 23/29 (79) | 21/29 (72) |
 TG | 19/31 (61) | 26/31 (84) | 23/31 (74) |
 TT | 109/192 (57) | 159/192 (83) | 133/192 (69) |