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Table 3 Demographic characteristics of KD and control cases and potential perinatal factors for KD development (frequencies, means and logistic regression with p-value, OR and 95% CI)

From: Breastfeeding and vitamin D supplementation reduce the risk of Kawasaki disease in a German population-based case-control study

 

KD cases

(n = 308)

Control cases

(n = 326)

Conditional logit – model (n = 454)

Unconditional logit - model (n = 542)

  

OR [95% CI]

p-value

Duration of pregnancy in weeks

 Average (±SD)

39 (±2.057)

39 (±1.944)

0.992 [0.891–1.105]

0.965 [0.883–1.050]

0.891

0.414

Parturitiona, n (%)

 Vaginal

128 (65.6)

194 (70.8)

1 (reference)

0.388

0.302

 Cesarean section

67 (34.4)

80 (29.2)

1.286 [0.727–2.274]

1.259 [0.813–1.953]

Birth weight in gram

 Average (±SD)

3340 (±527.052)

3383 (±537.734)

0.999 [0.999–1.000]

0.999 [0.999–1.000]

0.715

0.399

 Range

1560 – 4960

1171 – 4910

  

Duration of breastfeeding, n (%)

  <  2 weeks

66 (21.4)

30 (9.2)

1 (reference)

0.013

0.001

  >  2 weeksb

242 (78.6)

296 (90.8)

0.471 [0.260–0.853]

0.415 [0.243–0.687]

Vitamin D supplementation in the first year of life, n (%)

 No

64 (20.8)

53 (16.3)

1 (reference)

0.782

0.051

 Yes

244 (79.2)

273 (83.7)

0.926 [0.537–1.595]

0.623 [0.383–0.995]

Duration of vitamin D supplementation in the first year of life in months

 Mean (±SD)

5.16 (±5.749)

6.03 (±5.596)

0.964 [0.931–0.998]

0.965 [0.935–0.995]

0.039

0.024

Regularity of vitamin D supplementationc, n (%)

 Irregular

65 (26.6)

55 (20.0)

1 (reference)

0.042

0.060

 Regular

179 (73.4)

220 (80.0)

0.559 [0.319–0.980]

0.642 [0.402–1.016]

  1. a not asked in n = 52 control cases vs. n = 113 KD cases, b includes partially breastfed children. crefers only to cases that received vitamin D