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Table 1 Laboratory data in HbSS patients vs. HbSC patients

From: Endocrine and metabolic complications in children and adolescents with Sickle Cell Disease: an Italian cohort study

Laboratory data

Hb SS

HbSC

P-value

Group (n = 38)

Group (n = 14)

HU > 1 years (%)

71% (27/38)

21.4% (3/14)

–

WBCs, 1000s

11.2 ± 4.31

6.76 ± 1.80

0.0001

WBCs, 1000s(mean 2016)

11.2 ± 3.32

7.18 ± 1.96

< 0.0001

Neutrophils, %

50.0 ± 12.1

49.9 ± 10.6

0.9835

Neutrophils, % (mean 2016)

49.1 ± 9.9

47.7 ± 8.3

0.4960

Hb, g/dl

9.0 ± 1.0

11.8 ± 1.2

< 0.0001

Hb, g/dl (mean 2016)

9.1 ± 0.9

11.6 ± 1.2

< 0.0001

Hb S, %

63.3 ± 14.2

46.7 ± 10.4

0.0005

Hb F, %

15.7 ± 7.8

7.0 ± 11.5

0.0003

Platelets, 1000s

421 ± 201

221 ± 100

0.0002

LDH, U/L

951.8 ± 216.5

582.4 ± 144.8

< 0.0001

  1. Data are reported as mean ± SD (standard deviation)
  2. Abbreviations: HbSS homozygous SS patients, HbSC double heterozygous SC patients, HU hydroxyurea, WBC white blood cells, Hb hemoglobin, LDH lactate dehydrogenase
  3. P-values statistically significant are printed in bold