Table 1 Study Characteristics
Author | Year Published | Number of Patients | Country | Design | Clinical Setting | Funding | Drop Outs | Inclusion Criteria | Exclusion Criteria | Age Range | LAMP Specimens | Timing of sampling | Reference Standard |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lee (14) | 2015 | 1574 | Vietnam, China & Korea | Retrospective cohort study | Suspected Meningitis | State Funded | 0 | Suspected Meningitis | > 5 years of age | < 5 years | CSF | Retrospective | qPCR |
Bourke (15) | 2015 | 148 | UK | Prospective cohort study | Paediatric ED | State Funded | 13 No consent | Suspected meningococcal infection | > 14 years of age | 17 days to 12 years | CSF, Blood, Swab | Prospective | qPCR Blood Culture |
McKenna(16) | 2010 | 267 | UK | Retrospective cohort study | Children’s Hospital | State Funded | 11 Excluded (> 18 years of age) | Suspected meningococcal infection | None | 7 days to 18 years | CSF Blood Swab | Retrospective | qPCR |