Skip to main content

Advertisement

Table 3 NRG1 variants frequency in Indonesian HSCR and population databases

From: NRG1 variant effects in patients with Hirschsprung disease

Variant HSCR patients Indonesian control 1000 Genomesμ ExACμ p-value
      vs. 1000 Genomes vs. ExAC
c.397G > C (p.V133 L) 0.009 0 0 0.0007 < 0.0001 < 0.0001
rs7834206 0.30 0.19 0.18 N/A < 0.0001 N/A
rs3735774 0.07 0.09 0.09 0.07 1 1
rs75155858 0.35 0.35 0.35 0.35 1 1
  1. *, a p-value of < 0.05 was considered significant; μ, East Asian ancestries; HSCR, Hirschsprung disease; N/A, not available