Table 4 Mortality and morbidities of late-onset sepsis in each subgroup and period
23–24 weeks’ gestation | Period I (n = 49) | Period II (n = 105) | Total (n = 154) | |||
LOS (n = 17) | Control (n = 32) | LOS (n = 26) | Control (n = 79) | LOS (n = 43) | Control (n = 111) | |
Mortality | 9 (52.9) | 13 (40.6) | 10 (38.5) | 13 (16.5) #,* | 19 (44.2) | 26 (23.4) # |
PDA | 17 (100) | 29 (90.6) | 26 (100) | 75 (94.8) | 43 (100) | 104 (93.7) |
NEC ≥ stage 2b | 3 (17.6) | 2 (6.3) | 7 (26.9) | 7 (8.9) # | 10 (23.3) | 9 (8.1) # |
BPD grade (≥ moderate) | 11 (100) | 15 (75.0) # | 12 (63.2) * | 49 (70.0) | 23 (76.7) | 64 (71.1) |
IVH ≥ stage 3 | 4 (23.5) | 11 (34.4) | 11 (42.3) | 28 (35.4) | 15 (34.9) | 39 (35.1) |
ROP ≥ stage 3 | 8 (50.0) | 11 (36.7) | 12 (52.2) | 33 (43.4) | 20 (51.3) | 44 (41.5) |
25–26 weeks’ gestation | Period I (n = 75) | Period II (n = 135) | Total (n = 210) | |||
LOS (n = 24) | Control (n = 51) | LOS (n = 12) | Control (n = 123) | LOS (n = 36) | Control (n = 174) | |
Mortality | 3 (12.5) | 5 (9.8) | 1 (8.3) | 11 (8.9) | 4 (11.1) | 16 (9.2) |
PDA | 23 (95.8) | 48 (94.1) | 11 (91.7) | 105 (85.4) | 34 (94.9) | 153 (87.9) |
NEC ≥ stage 2b | 1 (4.2) | 2 (3.9) | 2 (16.7) | 6 (4.9) | 3 (8.3) | 8 (4.6) |
BPD grade (≥ moderate) | 12 (54.5) | 32 (68.1) | 9 (81.8) | 47 (42.0) #,* | 21 (63.6) | 79 (49.7) |
IVH ≥ stage 3 | 3 (12.5) | 5 (9.8) | 1 (8.3) | 16 (13.0) | 4 (11.1) | 12 (12.1) |
ROP ≥ stage 3 | 11 (47.8) | 21 (42.0) | 6 (54.5) | 27 (23.1) #,* | 17 (50) | 48 (28.7) # |
Total, 23–26 weeks’ gestation | Period I (n = 124) | Period II (n = 240) | Total (n = 364) | |||
LOS (n = 41) | Control (n = 83) | LOS (n = 38) | Control (n = 202) | LOS (n = 79) | Control (n = 285) | |
Mortality | 12 (29.3) | 18 (21.7) | 11 (28.9) | 24 (11.9) #* | 23 (29.1) | 42 (14.7) # |
PDA | 40 (97.6) | 77 (92.8) | 37 (97.4) | 180 (89.1) | 77 (97.5) | 257 (90.2) # |
NEC ≥ stage 2b | 4 (9.8) | 4 (4.8) | 9 (23.7) | 13 (6.4) # | 13 (16.5) | 17 (6.0) # |
BPD grade (≥ moderate) | 23 (69.7) | 47 (70.1) | 21 (70) | 96 (52.7) * | 44 (69.8) | 143 (57.3) |
IVH ≥ stage 3 | 7 (17.1) | 16 (19.3) | 12 (31.6) | 44 (21.8) | 19 (24.1) | 60 (21.1) |
ROP ≥ stage 3 | 19 (48.7) | 32 (40) | 18 (52.9) | 60 (31.1) # | 37 (50.7) | 92 (33.7) # |