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Table 1 Case-control studies included in the research

From: Effect of childhood BMI on asthma: a systematic review and meta-analysis of case-control studies

Author Sample country Exposure categorization method Age group (year) Asthma Diagnosis Publication year Time duration Quality Score
Gennuso & et al. [48] Case:85 (USA) Reference data Normal <85, Obese: ≥ 85th <95th.Very obese: ≥ 95th [15] Case: 4-16 Physician diagnosed asthma 1998 N/R 80
Control:86 Control:4-16
Vignolo & et al. [49] Case:554 (Italy) BMI- (SDS) units (z-score) Case: 2.2-16.1 Physician diagnosed asthma 2005 Case: January –December 2001 80
Control:625 Control: 2.4–16.3 Control: April-May 2001
Mansell & et al. [50] Case:134 (USA) Overweight >85th and non overweight <85th (CDC growth charts) Case: 12-18 Physician diagnosed asthma 2006 N/R 80
Control:82 Control:12-18
Vargas & et al. [51] Case:213 (USA) Risk for overweight ≥ 85th-<95th/ overweight ≥ 95th (CDC growth charts ) Case: 3-5 Physician diagnosed asthma 2007 November 2000-December 2003 90
Control:816 Control:3-5
Careneiro bertolace & et al. [52] Case:231 (Brazil) Overweight :≥ 85th and Obese: ≥ 95th (CDC growth charts) Case: 13-14 Completed ISAAC questionnaire by adolescence 2008 March-December 2005 80
Control:190 Control:13-14
Henkin & et al. [40] Case:94 (USA) (Asian patient) Underweight<20%, normal 20-85%, risk for overweight 85-95% & Overweight >95% (CDC growth charts Case: 4-18 Physician-diagnosed asthma 2008 N/R 100
Control:94 Control:4-18
Walders-Abramson & et al. [53] Case:59 (USA) ≥95th obese,” 85th–95th “overweight,”15 and <85th “normal weight (CDC growth charts) Case: 10-16 Physician-diagnosed asthma 2009 December 2005-July 2007 80
Control:59 Control:10-16
Tsai & et al. [54] Case:27 (USA) Age- and sex-specific cut-off points for childhood by (IOTF) Case: 9-11 Parent reported according physician-diagnosed asthma and meds use 2012 2004-2006 80
Control:27 Control:9-11
Ahmadi-afshar & et al. [55] Case:200 (Iran) Overweight : BMI>85th and Obese BMI>95th (CDC growth charts) Case: 6-15 Physician-diagnosed asthma 2013 March-September 2010 80
Control:200 Control:6-15
Scepanovic & et al. [16] Case:354 (Montenegro) Based on the BMI percentile values Case: 6-15 Physician-diagnosed asthma 2013 N/R 70
Control:354 Control: 6-15
Nahhas & et al. [43] Case:632 (Saudi Arabia) Underweight <5th, Normal 5th-85th, Overweight 85th-94th & obese ≥ 95 (CDC growth charts) Case: 6-8 Complete a ISAAC questionnaire by parent 2014 N/R 90
Control:632 Control: 6-8
Forno & et al. [42] Case:351 (Puerto Rico) BMI z scores based on CDC growth charts Case: 6-14 Physician-diagnosed asthma 2014 March 2009 -June 2010 90
Control:327 Control: 6-14
Papoutsakis & et al. [41] Case:217 (Greece ) Age- and sex-specific cut-off points for childhood by (IOTF) Case: 5-11 Physician-diagnosed asthma 2015 November 2007-September 2010 90
Control:297 Control: 5-11
Rice & et al. [56] Case:287 (Peru) Age- and sex-specific cut-off points for childhood by (IOTF) Case: 9-19 Physician-diagnosed asthma 2015 N/R 80
Control:96 Control: 9-19
Groth & et al. [57] Case:61 (USA) Underweight <5th, Normal ≥ 5th and < 85th, Overweight ≥ 85th and < 95th obese ≥ 95th (CDC growth charts) Case: 12-15 Physician-diagnosed asthma 2016 2002-2004 90
Control:484 Control: 12-15
Lawson& et al. [44] Case:78 (Canada) Age- and sex-specific cut-off points for childhood by (IOTF) Case: 6-14 Physician-diagnosed asthma 2017 2011 100
Control:451 Control: 6-14
  1. N/R Not reported