Table 2 Clinical manifestations of 198 patients with dengue infection, including 38 with severe disease
Variables | Non-severe (n = 160) | Severe (n = 38) | p value |
|---|---|---|---|
Demographics | |||
 Male (n, %) | 84 (52.5) | 23 (60.5) | 0.372 |
Age: 28Â days to 1Â year (n, %) | 40 (25.0) | 16 (42.1) | Â |
 ≥ 1 year to < 5 years | 45 (28.1) | 14 (36.8) | 0.012 |
 ≥ 5 years to < 16 years | 75 (46.9) | 8 (21.1) |  |
History/symptoms | |||
 Number of days of fever | 4.31 | 4.10 | 0.683 |
 Vomiting (n, %) | 94 (58.7) | 15 (39.4) | 0.032 |
 Abdominal pain (n, %) | 75 (46.8) | 9 (23.6) | 0.012 |
 Headache or retro-orbital pain (n, %) | 63 (39.3) | 8 (21) | 0.101 |
Clinical parameters | |||
 Rash (n, %) | 18 (11.2) | 1 (2.6) | 0.153 |
 Temperature (°C) | 38.76 | 38.63 | 0.234 |
 Pulse/min | 131.49 | 152.26 | < 0.001 |
 Capillary refill time | 2.03 | 2.24 | 0.001 |
 Respiratory rate | 38.40 | 46.42 | 0.002 |
 Liver enlargement (n, %) | 64 (40.0) | 22 (57.8) | 0.127 |
 Glasgow Coma Score | 14.60 | 13.42 | 0.003 |
Laboratory parameters | |||
 Haematocrit (%) | 32.56 | 28.84 | 0.004 |
 Platelets (per 103/μl) | 267.87 | 294.16 | 0.477 |
 White blood cells (per103/μl) | 9.46 | 14.25 | 0.006 |
 Neutrophils | 5.64 | 8.01 | 0.46 |
 Lymphocytes | 2.76 | 5.14 | < 0.001 |
 Urea (mmol/L) | 4.64 | 4.95 | 0.712 |
 Creatinine (μmol/l) | 68.29 | 68.71 | 0.932 |
 Alanine transaminase, IU/l | 78.99 | 177.08 | 0.002 |
 Urine protein mg/dL | 12.34 | 24.13 | 0.088 |
 Urine red blood cells | 2.84 | 10.32 | 0.009 |