Table 2 Characteristics according to the serum 25OHD level subgroups
From: Vitamin D in children with growth hormone deficiency due to pituitary stalk interruption syndrome
25OHD, ng/mL | 25OHD ≤ 12 | 13 < 25OHD ≤ 19 | 20 < 25OHD ≤ 30 | 25OHD > 30 | |||||
|---|---|---|---|---|---|---|---|---|---|
n = 2 | n = 9 | n = 15 | n = 24 | p | |||||
Boys | 0 | 0% | 3 | 33% | 7 | 47% | 18 | 75% | 0.04 |
Girls | 2 | 100% | 6 | 67% | 8 | 53% | 6 | 25% | |
Isolated GH deficiency | 1 | 50% | 6 | 67% | 4 | 27% | 11 | 46% | 0.2 |
Multiple HP deficiency | 1 | 50% | 3 | 33% | 11 | 73% | 13 | 54% | |
Sunny season | 0 | 0% | 0 | 0% | 4 | 27% | 11 | 46% | 0.01 |
Cold season | 2 | 100% | 6 | 100% | 11 | 73% | 13 | 54% | |
Mean ± SD | Mean ± SD | Mean ± SD | Mean ± SD | ||||||
Age at diagnosis, years | 13.5 ± 4.5 | 4.7 ± 5.1 | 6.5 ± 6.7 | 4.4 ± 2.8 | 0.1 | ||||
Bone age, years | 12 ± 5 | 3.6 ± 5.6 | 3.2 ± 3.5 | 2.5 ± 1.9 | 0.1 | ||||
Height, SDS | −2.7 ± −2.7 | −2.6 ± 0.6 | −3 ± 1.2 | −2.8 ± 1.5 | 0.9 | ||||
BMI, SDS | 1.3 ± 0.8 | 0.4 ± 1.6 | 0.3 ± 2.3 | 0 ± 1.6 | 0.6 | ||||
Growth rate, SDS | − 2.6 ± 0 | − 2.4 ± 0.6 | − 2.7 ± 1.2 | − 3 ± 1.2 | NS | ||||
IGF1, SDS | −4.7 ± 0 | −2.4 ± 1.8 | −3.9 ± 0.8 | −3.6 ± 1 | NS | ||||