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Table 2 Ophthalmologic outcome of historical cohort

From: Study protocol: safety and efficacy of propranolol 0.2% eye drops in newborns with a precocious stage of retinopathy of prematurity (DROP-ROP-0.2%): a multicenter, open-label, single arm, phase II trial

ROP progression

Any stage ROP

Stage 1 ROP at first visit

Newborns, n (%)

248

237 (95.6)

Aggressive Posterior ROP, n (%)

3 (1.2)

Stage ≥2 at first examination, n (%)

8 (3.2)

Stage 1 ROP at first examination, n (%)

237 (95.6)

Stage 2, n (%)

172 (69.3)

165 (69.6)

Stage 3, n (%)

72 (29.0)

68 (28.7)

Stage 2 or 3 ROP with plus, n (%)

63 (25.4)

58 (24.5)

Stage 4 ROP, n (%)

4 (1.6)

4 (1.7)

Stage 5 ROP, n (%)

1 (0.4)

1 (0.4)

Treatment with laser photocoagulation, n (%)

47 (18.9)

45 (19.0)

Treatment with bevacizumab, n (%)

30 (12.1)

27 (11.4)

Vitrectomy, n (%)

4 (1.6)

4 (1.7)

Cryotherapy, n (%)

1 (0.4)

1 (0.4)