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Table 1 Comparisons of infant and perinatal characteristics and neonatal outcomes among networks (ANZNN, CNN, SNQ) for very low gestational age cohort and very low birth weight cohort derived from network admissions 2008–2011

From: Comparing very low birth weight versus very low gestation cohort methods for outcome analysis of high risk preterm infants

  Very low gestational age Very low birth weight
Networks ANZNN CNN SNQ P-value ANZNN CNN SNQ P-value
Total number 13,586 12,167 3427   11,307 10,327 2701  
Infant and Perinatal Characteristics
 Gestational age, mean(SD) 28.5(2.2) 28.3(2.2) 28.3(2.4) <0.0001 28.3(2.6) 28.2(2.6) 27.9(2.7) <0.0001
 Birth weight, mean(SD) 1232 396) 1209 (387) 1234 (424) <0.0001 1082 (274) 1068(267) 1055 (291) <0.0001
 Male sex 7345 (54.1) 6617 (54.5) 1838 (53.6) 0.6619 5762 (51.0) 5290(51.3) 1372 (50.8) 0.8571
 Small for gestational age 1249 (9.2) 1133 (9.3) 317 (9.3) 0.9515 2369 (21.0) 2082(20.2) 521 (19.3) 0.0999
 Singleton 9532 (70.2) 8417 (69.3) 2441 (71.3) 0.0478 7901 (69.9) 7099(68.8) 1930 (71.5) 0.016
 Surfactant required 7336 (54.1) 7179 (59.0) 1941 (56.8) <0.0001 6442 (57.1) 6233(60.4) 1649 (61.3) <0.0001
 Antenatal steroid use 12,902 (95.1) 10,156 (86.6) 3278 (95.7) <0.0001 10,723 (95.0) 8520(85.7) 2581 (95.6) <0.0001
 Caesarean 8478 (62.7) 7117 (59.0) 2086 (61.2) <0.0001 7311 (65.0) 6565(64.1) 1679 (62.7) 0.0613
 Presentation (vertex) 8676 (65.4) 7307 (64.7) 2209 (65.7) 0.3872 7099 (64.2) 6004(63.0) 1720 (65.3) 0.0353
 Maternal age, mean(SD) 29.8 (6.4) 30.5 (5.9) 29.9 (6.5) <0.0001 29.7 (6.5) 30.5(6.0) 29.8 (6.6) <0.0001
Neonatal Outcomes
 Mortality 987 (7.3) 986 (8.1) 265 (7.7) 0.0407 948 (8.4) 945(9.2) 252 (9.3) 0.0841
 Severe neurological injury 758 (5.6) 1409 (9.4) 220 (6.4) <0.0001 711 (6.3) 1293(10.1) 202(7.5) <0.0001
 Severe retinopathy of prematurity 496 (3.7) 592 (4.9) 146 (4.3) <0.0001 487 (4.3) 596(5.8) 144 (5.3) <0.0001
 Necrotising enterocolitis 591 (4.4) 690 (5.7) 143 (4.2) <0.0001 566 (5.0) 641(6.2) 134 (5.0) 0.0002
 Chronic lung disease 2381 (17.5) 2597 (21.3) 629 (18.4) <0.0001 2233 (19.8) 2472(23.9) 586 (21.7) <0.0001
 Composite adverse outcome 3893 (28.7) 4564 (36.5) 1043 (30.4) <0.0001 3649 (32.3) 4272(40.3) 962 (35.6) <0.0001
 Nosocomial Infection 2008 (14.8) 2188 (18.0) 484 (14.1) <0.0001 1869 (16.5) 2069(20.0) 454 (16.8) <0.0001
  1. N (%) are shown unless specified
  2. Notes: the reported p-values were based on chi-square tests for categorical variables, and F tests for continuous variables. Composite adverse outcome is defined as: death or any major morbidities including chronic lung disease, severe neurological injury, necrotising enterocolitis, severe retinopathy. Nosocomial infection is not included
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BMC Pediatrics

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