Table 3 Associations between infant weight gain and allergic outcomes by 18 months
From: Effects of infant weight gain on subsequent allergic outcomes in the first 3 years of life
Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 | Q u arti l e 1 | Quartile 2 | Q uartile 3 | Q u arti le 4 | |||
|---|---|---|---|---|---|---|---|---|---|---|
Period of weight gain | Allergic outcomes | N(%) | N(%) | N(%) | N(%) | Reference group | Adjusted OR (95% CI) | Adjusted OR (95% CI) | Adjusted OR (95% CI) | p-trend |
0 to 3 months | Wheeze with a positive skin prick test | 1 (0.6) | 5 (3.0) | 2 (1.3) | 11 (7.6) | 1.00 | 1.4 (0.1–17.9) | 1.3 (0.1–18.6) | 4.5 (0.4–53.4) | 0.2 |
Prolonged rhinitis with a positive skin prick test | 3 (1.9) | 1 (0.7) | 2 (1.4) | 7 (5.2) | 1.00 | 0.2 (0.0–3.0) | 0.2 (0.0–3.4) | 1.7 (0.2–14.5) | 0.2 | |
Atopic eczema with a positive skin prick test | 5 (3.0) | 4 (2.4) | 2 (1.3) | 9 (6.2) | 1.00 | 0.4 (0.1–2.4) | 0.3 (0.0–2.2) | 0.8 (0.1–4.9) | 0.8 | |
Positive skin prick test | 28 (14.1) | 25 (14.0) | 12 (6.7) | 34 (19.3) | 1.00 | 1.1 (0.5–2.4) | 0.6 (0.2–1.4) | 1.7 (0.7–3.9) | 0.5 | |
3 to 6 months | Wheeze with a positive skin prick test | 5 (3.2) | 4 (2.5) | 2 (1.3) | 3 (1.9) | 1.00 | 1.1 (0.1–8.5) | 0.5 (0.0–6.5) | 1.8 (0.3–12.4) | 0.7 |
Prolonged rhinitis with a positive skin prick test | 0 (0) | 4 (2.8) | 4 (2.9) | 4 (2.9) | 1.00 | # | # | # | # | |
Atopic eczema with a positive skin prick test | 5 (3.1) | 3 (1.8) | 1 (0.7) | 3 (2.0) | 1.00 | 1.6 (0.2–10.6) | # | 1.0 (0.1–8.7) | 0.6 | |
Positive skin prick test | 31 (17.6) | 30 (16.8) | 21 (12.4) | 14 (8.3) | 1.00 | 1.4 (0.7–3.0) | 0.9 (0.4–2.0) | 0.6 (0.2–1.4) | 0.1 | |
6 to 9 months | Wheeze with a positive skin prick test | 3 (1.9) | 2 (1.2) | 5 (3.1) | 3 (2.0) | 1.00 | 0.3 (0.0–3.6) | 1.6 (0.3–9.7) | 0.6 (0.1–7.9) | 0.9 |
Prolonged rhinitis with a positive skin prick test | 2 (1.4) | 1 (0.7) | 3 (2.1) | 1 (0.8) | 1.00 | 1.0 (0.1–12.6) | 0.7 (0.1–9.6) | 0.7 (0.0–11.4) | 0.8 | |
Atopic eczema with a positive skin prick test | 5 (3.2) | 4 (2.6) | 1 (0.7) | 1 (0.7) | 1.00 | 2.4 (0.3–16.7) | 0.6 (0.0–7.0) | # | 0.3 | |
Positive skin prick test | 30 (17.9) | 26 (15.4) | 22 (13.2) | 16 (9.7) | 1.00 | 0.5 (0.2–1.1) | 0.5 (0.2–1.0) | 0.3 (0.1–0.7) | <0.01 | |
9 to 12 m o n th s | Wheeze with a positive skin prick test | 3 (1.9) | 1 (0.6) | 3 (1.9) | 0 (0) | 1.00 | 0.7 (0.1–9.6) | 1.8 (0.2–16.1) | # | 0.5 |
Prolonged rhinitis with a positive skin prick test | 1 (0.7) | 0 (0) | 0 (0) | 2 (1.3) | 1.00 | # | # | # | # | |
Atopic eczema with a positive skin prick test | 3 (2.0) | 2 (1.3) | 1 (0.7) | 3 (2.0) | 1.00 | 0.6 (0.0–7.0) | 0.4 (0.0–4.9) | # | 0.2 | |
Positive skin prick test | 34 (20.0) | 26 (15.8) | 12 (7.3) | 20 (11.3) | 1.00 | 0.9 (0.4–1.8) | 0.4 (0.2–0.96) | 0.5 (0.2–1.2) | 0.03 | |
12 to 15 months | Wheeze with a positive skin prick test | 0 (0) | 3 (1.7) | 0 (0) | 1 (0.6) | 1.00 | # | # | # | # |
Prolonged rhinitis with a positive skin prick test | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 1.00 | # | # | # | # | |
Atopic eczema with a positive skin prick test | 1 (0.6) | 0 (0) | 0 (0) | 2 (1.2) | 1.00 | # | # | # | # | |
Positive skin prick test | 32 (17.7) | 25 (14.3) | 19 (11.2) | 20 (11.3) | 1.00 | 0.7 (0.3–1.4) | 0.5 (0.2–1.0) | 0.4 (0.2–0.8) | <0.01 | |