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Table 1 Demographic and clinical characteristics of 642 infants included in the cohort study. Numbers in first columns of each group specify the number of infants with obtained data

From: Weight-for-length, early weight-gain velocity and atopic dermatitis in infancy and at two years of age: a cohort study

 

Recruited from bronchiolitis trial (N = 404)

Recruited from the general population (N = 238)

 
 

No.

  

No.

  

P value

Male sex, No. (%)

404

240

(59)

238

133

(56)

.2

Age at enrolment, mean (min, max), months

404

4.2

(0.2, 12.0)

238

6.6

(1.0, 13.4)

<.001

Age at two-year follow-up visit, mean (min, max), months

294

24.6

(19.0, 35.2)

205

24.5

(17.5, 35.2)

.83

Father Caucasian, No. (%)

287

266

(93)

199

184

(93)

.53

Mother Caucasian, No. (%)

289

263

(91)

202

192

(95)

.06

High parental education,a No. (%)

351

245

(70)

238

219

(92)

<.001

Low parental income,b No. (%)

294

26

(9)

203

5

(3)

.002

Firstborn child, No. (%)

294

66

(22)

205

101

(61)

<.001

One or more sibling living at home, No. (%)

289

251

(87)

200

118

(59)

<.001

Pet ownership,c No. (%)

281

85

(30)

201

46

(23)

.05

Parental atopy,d No. (%)

293

213

(73)

205

152

(74)

.40

Maternal atopy

293

150

(51)

205

112

(55)

.25

Paternal atopy

293

120

(41)

205

86

(42)

.45

Exposed to in-door smoking at home, No. (%)

293

7

(2)

199

1

(0.5)

.10

Gestational age, mean (min, max), weeks

302

38.7

(26, 42)

223

39.6

(28, 42)

<.001

Exclusive breastfeeding duration, mean (SD), months

278

4.5

(2.4)

193

4.8

(2.2)

.14

Any breastfeeding, mean (SD), months

280

8.6

(5.3)

193

10.6

(5.6)

<.001

Vitamin D level at enrolment, mean (min, max), nmol/l

366

52.9

(6.0, 132.0)

229

66.5

(6.0, 120.5)

<.001

Vitamin D level two-year follow-up visit, mean (min, max), nmol/l

259

66.3

(6.0, 142.9)

191

67.8

(16.6, 130.0)

.39

Filaggrin mutation,e No. (%)

361

26

(7)

203

16

(8)

.44

TEWLf at enrolment, median (Q1, Q3), g/m2/h

NA

NA

NA

165

8.20

(5.90, 10.43)

NA

TEWLf at two-year follow-up visit, median (Q1, Q3), g/m2/h

204

5.98

(4.28, 9.20)

156

5.08

(3.28, 7.58)

.04

  1. aOne or both parents reporting education beyond 12 (or 13) years schooling
  2. b< 500,000 NOK per year, approx 60,000 USD
  3. cHaving dog, cat, rabbit, hamster, guinea pig and/or parakeet
  4. dMother and/or father reporting asthma, allergic rhinitis, atopic dermatitis, food allergy and/or urticaria
  5. eR501X, 2282del4, R2447X, S3247X, all heterozygeous
  6. fMeasured on lateral part of upper arm
  7. TEWL transepidermal water loss ,Q1 lower quartile, Q3 upper quartile, NA not assessed