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Table 1 Demographic and clinical characteristics of 642 infants included in the cohort study. Numbers in first columns of each group specify the number of infants with obtained data

From: Weight-for-length, early weight-gain velocity and atopic dermatitis in infancy and at two years of age: a cohort study

  Recruited from bronchiolitis trial (N = 404) Recruited from the general population (N = 238)  
  No.    No.    P value
Male sex, No. (%) 404 240 (59) 238 133 (56) .2
Age at enrolment, mean (min, max), months 404 4.2 (0.2, 12.0) 238 6.6 (1.0, 13.4) <.001
Age at two-year follow-up visit, mean (min, max), months 294 24.6 (19.0, 35.2) 205 24.5 (17.5, 35.2) .83
Father Caucasian, No. (%) 287 266 (93) 199 184 (93) .53
Mother Caucasian, No. (%) 289 263 (91) 202 192 (95) .06
High parental education,a No. (%) 351 245 (70) 238 219 (92) <.001
Low parental income,b No. (%) 294 26 (9) 203 5 (3) .002
Firstborn child, No. (%) 294 66 (22) 205 101 (61) <.001
One or more sibling living at home, No. (%) 289 251 (87) 200 118 (59) <.001
Pet ownership,c No. (%) 281 85 (30) 201 46 (23) .05
Parental atopy,d No. (%) 293 213 (73) 205 152 (74) .40
Maternal atopy 293 150 (51) 205 112 (55) .25
Paternal atopy 293 120 (41) 205 86 (42) .45
Exposed to in-door smoking at home, No. (%) 293 7 (2) 199 1 (0.5) .10
Gestational age, mean (min, max), weeks 302 38.7 (26, 42) 223 39.6 (28, 42) <.001
Exclusive breastfeeding duration, mean (SD), months 278 4.5 (2.4) 193 4.8 (2.2) .14
Any breastfeeding, mean (SD), months 280 8.6 (5.3) 193 10.6 (5.6) <.001
Vitamin D level at enrolment, mean (min, max), nmol/l 366 52.9 (6.0, 132.0) 229 66.5 (6.0, 120.5) <.001
Vitamin D level two-year follow-up visit, mean (min, max), nmol/l 259 66.3 (6.0, 142.9) 191 67.8 (16.6, 130.0) .39
Filaggrin mutation,e No. (%) 361 26 (7) 203 16 (8) .44
TEWLf at enrolment, median (Q1, Q3), g/m2/h NA NA NA 165 8.20 (5.90, 10.43) NA
TEWLf at two-year follow-up visit, median (Q1, Q3), g/m2/h 204 5.98 (4.28, 9.20) 156 5.08 (3.28, 7.58) .04
  1. aOne or both parents reporting education beyond 12 (or 13) years schooling
  2. b< 500,000 NOK per year, approx 60,000 USD
  3. cHaving dog, cat, rabbit, hamster, guinea pig and/or parakeet
  4. dMother and/or father reporting asthma, allergic rhinitis, atopic dermatitis, food allergy and/or urticaria
  5. eR501X, 2282del4, R2447X, S3247X, all heterozygeous
  6. fMeasured on lateral part of upper arm
  7. TEWL transepidermal water loss ,Q1 lower quartile, Q3 upper quartile, NA not assessed