Analgesic antipyretic use among young children in the TEDDY study: no association with islet autoimmunity

BMC Pediatrics

Table 2 Summary of treatment episodes associated with fever and/or infection

			US	Finland	Germany	Sweden	Total Cohort	Country differences
								U-F	U-G	U-S	F-G	F-S	G-S
Total episodes		n	25,340	7427	2091	17,285	52,643
Acetaminophen	Fever and infection	n	4272	2907	983	9224	17,386	<0.001	<0.001	<0.001	<0.001	<0.001	0.003
	Fever or infection		6557	1277	311	3421	12,066
	No fever and no infection	n	7348	841	141	1953	10,283	<0.001	<0.001	<0.001	<0.001	0.006	0.01
NSAID	Fever and infection	n	2680	1273	477	1572	6002	<0.001	<0.001	<0.001	<0.001	<0.001	0.024
	Fever or infection	n	2472	717	125	330	3644
	No fever and no infection	n	1841	167	38	74	2120	<0.001	<0.001	<0.001	0.174	<0.001	0.041

Country differences: U = US, G = Germany, F = Finland, S = Sweden, Country differences described as p-value for difference between the respective countries

ISSN: 1471-2431