Skip to main content

Table 3 Gross Motor Function Measure and Muscle tone before and after stem cell transplantation

From: Outcomes of autologous bone marrow mononuclear cells for cerebral palsy: an open label uncontrolled clinical trial

  Baseline
Mean [95% CI]
3 months post-transplantation
Mean [95% CI]
6 months post-transplantation
Mean [95% CI]
Total GMFM-88 16.7 [12.3; 21.1] 38.9 [32.2; 45.6]* 41.8 [34.8; 48.7]*
A. Lying & rolling 48.4 [41.2; 55.5] 87.8 [83.5; 92.1]* 91.7 [88.0; 95.3]*
B. Sitting 24.0 [16.5; 31.5] 55.1 [46.0; 64.3]* 59.5 [50.4; 68.7]*
C. Crawling & kneeling 8.7 [3.5; 13.8] 30.2 [18.9; 41.5]* 33.3 [21.4; 45.2]*
D. Standing 4.0 [0.9; 7.1] 17.9 [10.1; 25.7]* 20.2 [11.5; 28.8]*
E. Walking, running & jumping 1.2 [0.1; 2.4] 5.8 [2.2; 9.5]** 6.5 [2.5; 10.4]**
GMFM-66 24.8 [21.4; 28.1] 38.2 [34.6; 41.8]* 40.0 [36.3; 43.6]*
GMFM-66 percentiles 31.7 [24.9; 38.5] 82.3 [76.0; 88.5]* 84.6 [78.3; 90.8]*
Modified ashworth score 3.4 [3.2; 3.6] 2.1 [1.9; 2.3]* 2.0 [1.8; 2.2]*
  1. *p-value < 0.0001 (paired t-test, compared to baseline)
  2. **p-value = 0.001 (paired t-test, compared to baseline)