Table 3 Comparison between different protocols and reference values in children using the TSA-II
Meier et al. 2001 | Blankenburg et al. 2010 | Van den Bosch et al. 2017 | |
|---|---|---|---|
Sample size | N = 101 | N = 176 | N = 69 |
Sex differences | Not tested (53 girls and 48 boys were included) | 88 males versus 88 females | 28 males versus 41 females |
Age differences | Not tested (Included children were 6–17 years old) | 3 different age groups; Age range 6–16 years | 4 different age groups; Age range 8–17 years |
QST technique | Thermal detection and pain and vibration sensation | Thermal and mechanical detection and pain | Thermal detection and pain |
Instructions for pain threshold | Not specified | ‘Aching’, ‘stinging’, or ‘burning’ | ‘Starts to feel painful’ |
Reaction time | Not obtained | Not obtained | Obtained |
Data transformation | None | Logarithmic data transformation | None |
Body site | Hand and foot | Face, hand and foot | Hand |
Time | Not described for the total protocol | 32.0 ± 3.5 min in adolescents (13–16 years) and 35.0 ± 6.2 min in children (9–12 years) | 14–18 min |