Table 1 Diagnostic findings for BP
Clinic | Blistering lesions on erythematous skin, with a prevailing acral distribution |
|---|---|
Histology | Subepidermal blister with a mixed perivascular infammatory infiltrate |
Direct immunofluorescence microscopy | Linear deposits of IgG and C3 along the basement membrane |
Indirect immunofluorescence microscopy on salt-split-skin | BP antibodies deposited primarily at the epidermal side of the induced blister |
ELISA | Presence of circulating antibodies against the 2 BP antigens (BP180 and BP230) |