Table 7 Pharmacokinetic parameters for intravenous ibuprofen by age category

Birth to < 6 mo.

1

51.18

69.14

49.83

0.167

1.8

619.97

1053.72

6 mo. to < 2 years.

(min, max)

5

71.15

(34.67, 95.20)

70.92

(34.67, 95.20)

59.24

(38.37, 92.02)

0.234

(0.167, 0.500)

1.78

(1.06, 2.35)

1172.5

(844.83, 1955.92)

2805.73

(2036.38, 3568.56)

2 yrs. to < 6 years.

(min, max)

12

79.19

(19.00, 109.50)

80.25

(22.96, 123.58)

64.18

(15.91, 96.31)

0.309

(0.167, 0.767)

1.48

(0.79, 2.87)

1967.27

(1098.93, 4744.56)

3695.76

(1850.84, 5410.57)

6 years. to < 16 years.

(min, max)

25

80.67

(40.00, 161.30)

85.73

(39.62, 162.03)

61.89

(31.03, 93.32)

0.212

(0.167, 667)

1.55

(0.79, 2.54)

4878.47

(998.60, 12536.67)

10314.21

(2638.76, 23964.19)