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Table 5 Summary of afebrile temperature

From: A multicenter, randomized, open-label, active-comparator trial to determine the efficacy, safety, and pharmacokinetics of intravenous ibuprofen for treatment of fever in hospitalized pediatric patients

 

Acetaminophen

Intravenous ibuprofen

Subjects Afebrile at 4 h Post-Dose

 Yes

40 (75%)

43 (91%)

 No

11 (21%)

3 (6%)

p-value

0.036

Time to Afebrile Temperature (hrs)

 N

53

47

 Number Censored

6 (11%)

2 (4%)

 Mean (SE)

3.3 (0.67)

2.2 (0.47)

 Median (95% CI)

1.5 (1.0, 2.5)

1.3 (1.0, 1.5)

 25%–75%

1.0–4.0

0.8–2.1

p-value

0.156

  1. CI confidence interval, Hrs hours, N number, SD standard deviation