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Table 2 Lipid profiles for pediatric untreated acute and IVIG-treated subacute and convalescent KD subjects and healthy and febrile pediatric controls

From: Differences in GlycA and lipoprotein particle parameters may help distinguish acute kawasaki disease from other febrile illnesses in children

Characteristic

Acute KD

2–10 days

(n = 75)

Subacute KD

13–24 days

(n = 36)

Early Convalescent KD

25–75 days

(n = 43)

Late Convalescent KD

9–49 months

(n = 20)

Acute Febrile Controls

Bacterial origin

(n = 12)

Acute Febrile Controls

Viral origin

(n = 36)

Healthy

Controls

(n = 48)

HDL-C, mg/dL

26 (19–33)

44 (39–47)

53 (48–58)

56 (52–65)

37 (32–41)

34 (28–39)

49 (42–54)

TG, mg/dL

78 (66–97)

104 (83–142)

79 (67–105)

68 (65–99)

86 (55–120)

63 (56–75)

93 (73–115)

LDL particles, nmol/L

 Total LDL-P

1513 (1228–1826)

1259 (766–1416)

984 (680–1115)

861 (705–1167)

1186 (934–1273)

1052 (916–1231)

1110 (948–1248)

 IDL-P

110 (65–159)

128 (56–176)

100 (44–143)

88 (63–118)

88 (65–117)

78 (55–107)

106 (71–145)

 Large LDL-P

116 (29–244)

472 (261–629)

415 (281–497)

339 (290–527)

299 (216–340)

99 (47–215)

558 (426–718)

 Small LDL-P

1230 (880–1574)

483 (392–677)

435 (331–532)

456 (291–536)

754 (549–973)

809 (688–996)

394 (190–531)

HDL particles, μmol/L

 Total HDL-P

18 (14–22)

28 (27–32)

32 (30–34)

33 (32–35)

23 (22–24)

23 (20–27)

30 (27–34)

 Large HDL-P

2.1 (1.4–3.1)

4.4 (3.3–5.4)

5.9 (4.6–7.6)

6.2 (4.8–8.5)

4.0 (2.8–6.2)

2.2 (1.3–3.2)

4.7 (3.8–5.8)

 Medium HDL-P

8.6 (4.7–12.8)

11.4 (9.8–13.9)

11.7 (10.6–14.5)

12.4 (9.6–14.2)

12.9 (9.0–15.9)

10.2 (7.9–12.9)

9.1 (5.8–12.7)

 Small HDL-P

6.8 (3.9–9.2)

11.8 (9.5–13.5)

13.6 (12.0–15.0)

13.9 (11.5–15.8)

4.5 (2.6–7.4)

10.5 (7.1–13.1)

16.2 (14.4–18.0)

VLDL particles, nmol/L

 Total VLDL-P

39 (23–62)

56 (30–82)

36 (24–63)

31 (23–56)

57 (21–75)

27 (19–35)

49 (31–69)

 Large VLDL-P

0.9 (0.6–1.7)

1.9 (1.2–5.0)

1.2 (0.8–2.1)

1.1 (0.6–1.4)

0.9 (0.4–1.5)

1.3 (0.9–1.5)

1.4 (0.9–2.8)

 Medium VLDL-P

4.5 (1.8–10.4)

15.3 (7.3–28.7)

8.8 (3.2–16.5)

5.2 (0.6–1.4)

3.7 (2.5–18.2)

4.1 (2.0–8.1)

9.1 (4.6–19.4)

 Small VLDL-P

31 (18–52)

29 (15–45)

31 (18–42)

26 (17–41)

46 (17–57)

19 (12–29)

35 (21–48)

LDL-P/HDL-P

92 (65–119)

41 (28–51)

29 (22–37)

27 (21–34)

50 (37–59)

45 (37–61)

38 (29–42)

  1. Median (IQR = Interquartile Range; 25th-75th percentile). LDL-C low density lipoprotein cholesterol, HDL-C high density lipoprotein cholesterol, TG triglycerides, LDL-P low density lipoprotein particle number, IDL-P intermediate density lipoprotein particle number, HDL-P high density lipoprotein particle number, VLDL-P very low density particle number. Acute KD samples were taken pre-IVIG treatment. All other KD samples were taken post-IVIG treatment