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Table 2 Lipid profiles for pediatric untreated acute and IVIG-treated subacute and convalescent KD subjects and healthy and febrile pediatric controls

From: Differences in GlycA and lipoprotein particle parameters may help distinguish acute kawasaki disease from other febrile illnesses in children

Characteristic Acute KD
2–10 days
(n = 75)
Subacute KD
13–24 days
(n = 36)
Early Convalescent KD
25–75 days
(n = 43)
Late Convalescent KD
9–49 months
(n = 20)
Acute Febrile Controls
Bacterial origin
(n = 12)
Acute Febrile Controls
Viral origin
(n = 36)
Healthy
Controls
(n = 48)
HDL-C, mg/dL 26 (19–33) 44 (39–47) 53 (48–58) 56 (52–65) 37 (32–41) 34 (28–39) 49 (42–54)
TG, mg/dL 78 (66–97) 104 (83–142) 79 (67–105) 68 (65–99) 86 (55–120) 63 (56–75) 93 (73–115)
LDL particles, nmol/L
 Total LDL-P 1513 (1228–1826) 1259 (766–1416) 984 (680–1115) 861 (705–1167) 1186 (934–1273) 1052 (916–1231) 1110 (948–1248)
 IDL-P 110 (65–159) 128 (56–176) 100 (44–143) 88 (63–118) 88 (65–117) 78 (55–107) 106 (71–145)
 Large LDL-P 116 (29–244) 472 (261–629) 415 (281–497) 339 (290–527) 299 (216–340) 99 (47–215) 558 (426–718)
 Small LDL-P 1230 (880–1574) 483 (392–677) 435 (331–532) 456 (291–536) 754 (549–973) 809 (688–996) 394 (190–531)
HDL particles, μmol/L
 Total HDL-P 18 (14–22) 28 (27–32) 32 (30–34) 33 (32–35) 23 (22–24) 23 (20–27) 30 (27–34)
 Large HDL-P 2.1 (1.4–3.1) 4.4 (3.3–5.4) 5.9 (4.6–7.6) 6.2 (4.8–8.5) 4.0 (2.8–6.2) 2.2 (1.3–3.2) 4.7 (3.8–5.8)
 Medium HDL-P 8.6 (4.7–12.8) 11.4 (9.8–13.9) 11.7 (10.6–14.5) 12.4 (9.6–14.2) 12.9 (9.0–15.9) 10.2 (7.9–12.9) 9.1 (5.8–12.7)
 Small HDL-P 6.8 (3.9–9.2) 11.8 (9.5–13.5) 13.6 (12.0–15.0) 13.9 (11.5–15.8) 4.5 (2.6–7.4) 10.5 (7.1–13.1) 16.2 (14.4–18.0)
VLDL particles, nmol/L
 Total VLDL-P 39 (23–62) 56 (30–82) 36 (24–63) 31 (23–56) 57 (21–75) 27 (19–35) 49 (31–69)
 Large VLDL-P 0.9 (0.6–1.7) 1.9 (1.2–5.0) 1.2 (0.8–2.1) 1.1 (0.6–1.4) 0.9 (0.4–1.5) 1.3 (0.9–1.5) 1.4 (0.9–2.8)
 Medium VLDL-P 4.5 (1.8–10.4) 15.3 (7.3–28.7) 8.8 (3.2–16.5) 5.2 (0.6–1.4) 3.7 (2.5–18.2) 4.1 (2.0–8.1) 9.1 (4.6–19.4)
 Small VLDL-P 31 (18–52) 29 (15–45) 31 (18–42) 26 (17–41) 46 (17–57) 19 (12–29) 35 (21–48)
LDL-P/HDL-P 92 (65–119) 41 (28–51) 29 (22–37) 27 (21–34) 50 (37–59) 45 (37–61) 38 (29–42)
  1. Median (IQR = Interquartile Range; 25th-75th percentile). LDL-C low density lipoprotein cholesterol, HDL-C high density lipoprotein cholesterol, TG triglycerides, LDL-P low density lipoprotein particle number, IDL-P intermediate density lipoprotein particle number, HDL-P high density lipoprotein particle number, VLDL-P very low density particle number. Acute KD samples were taken pre-IVIG treatment. All other KD samples were taken post-IVIG treatment